Protein Alignment Sh and Shal

DIOPT Version :10

• Sequence 1: NP_728123.1
• Gene: Sh / 32780
• FlyBaseID: FBgn0003380
• Length: 655
• Species: Drosophila melanogaster
• Sequence 2: XP_061502009.1
• Gene: Shal / 1270054
• VectorBaseID: AGAMI1_007411
• Length: 579
• Species: Anopheles gambiae
• Alignment Length: 585
• Identity: 183/585 - (31%)
• Similarity: 287/585 - (49%)
• Gaps: 138/585 - (23%)

  Fly    97 ERVVINVSGLRFETQLRTLNQFPDTLLGDPARRLRYFDPLRNEYFFDRSRPSFDAILYYYQSGGR 161
            |:::|||||.||||...|:.::||||||...|.. ::|....||||||....|..||.||:: |:
Mosquito    41 EKLIINVSGRRFETWRTTVEKYPDTLLGSNERDF-FYDEDSKEYFFDRDPDIFRHILNYYRT-GK 103

  Fly   162 LRRPVNVPLDVFSEEIKFY-----ELGDQAINKFREDEGFIKEEERPLPD--------------N 207
            |..|.:..|..:.||:.|:     .:||.....:|:.:.  :..||.:.|              |
Mosquito   104 LHYPRHECLLSYDEELAFFGIMPDVIGDCCYEDYRDRKR--ENAERLMDDKLSENSDNNLQQLTN 166

  Fly   208 EKQRKVWLLFEYPESSQAARVVAIISVFVILLSIVIFCLETLP------------EFKHYKVFNT 260
            .:|| :|..||.|.:|.||.|...::.|.|.:|::...:||:|            ..:.||:.
Mosquito   167 IRQR-MWRAFENPHTSTAALVFYYVTGFFIAVSVMANVVETVPCGVRPGRAGTLSCGERYKIV-- 228

  Fly   261 TTNGTKIEEDEVPDITDPFFLIETLCIIWFTFELTVRFLACPNKLNFCRDVMNVIDIIAIIPYFI 325
                              ||.::|.|::.||.|..:|..|.|.:..|.|.||::||::||:||:|
Mosquito   229 ------------------FFCLDTACVMIFTAEYLLRLFAAPCRCKFVRSVMSIIDVVAILPYYI 275

  Fly   326 TLATVVAEEEDTLNLPKAPVSPQDKSSNQAMSLAILRVIRLVRVFRIFKLSRHSKGLQILGRTLK 390
            .|.                ::..|..|...::|      |:.|||||||.||||:||:|||.|||
Mosquito   276 GLG----------------ITDNDDVSGAFVTL------RVFRVFRIFKFSRHSQGLRILGYTLK 318

  Fly   391 ASMRELGLLIFFLFIGVVLFSSAVYFAEAGSENSFFKSIPDAFWWAVVTMTTVGYGDMTPVGVWG 455
            :...|||.|:|.|.:.:::|::.:::||...:.:.|.|||.|||:.:|||||:|||||.|..:.|
Mosquito   319 SCASELGFLVFSLAMAIIIFATVMFYAEKNVDGTNFTSIPAAFWYTIVTMTTLGYGDMVPETIAG 383

  Fly   456 KIVGSLCAIAGVLTIALPVPVIVSNFNYFYHRETDQEEMQSQNFNHVTSCPYLPGTLGQHMKKSS 520
            ||||.:|:::|||.||||||||||||:..||:....::.::|                   :|:.
Mosquito   384 KIVGGVCSLSGVLVIALPVPVIVSNFSRIYHQNQRADKRKAQ-------------------RKAR 429

  Fly   521 LSESSSDMMDLDDGVESTPGLTETHPGRSAVAPFLGAQQQQQQPVASSLS-MSIDK--------Q 576
            |:.                 :.....|.||.  |...::..:..:|:..| :.:|.        :
Mosquito   430 LAR-----------------IRIAKAGASAA--FASKKKAAESRLAAQESGIELDDNYNDEDIFE 475

  Fly   577 LQHP--LQQLTQTQLYQQQQQQQQQQQNGFKQQQQQTQQQLQQQQSHTINASAAAATSGSGSSGL 639
            |||.  |:.|.:|.  .::..:.:.|.||  |.::..........||:.|       :.:|::||
Mosquito   476 LQHHHLLRCLEKTT--DREFVELETQYNG--QTKRPGSPSPMASPSHSAN-------TATGATGL 529

  Fly   640  639
            Mosquito   530  529

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sh	NP_728123.1	BTB_POZ	97..223	CDD:453885	50/144 (35%)
		Ion_trans	226..488	CDD:459842	105/273 (38%)
Shal	XP_061502009.1	None