Protein Alignment Sh and kcnk10

DIOPT Version :10

• Sequence 1: NP_728123.1
• Gene: Sh / 32780
• FlyBaseID: FBgn0003380
• Length: 655
• Species: Drosophila melanogaster
• Sequence 2: XP_002933240.1
• Gene: kcnk10 / 100497885
• XenbaseID: XB-GENE-950562
• Length: 545
• Species: Xenopus tropicalis
• Alignment Length: 315
• Identity: 65/315 - (20%)
• Similarity: 108/315 - (34%)
• Gaps: 83/315 - (26%)

  Fly   366 LVRVFRIFKLSRHSKGLQILGRTLKASMRELGLLIF-------FLFIGVVLFSSAVYFAEAGSEN 423
            :.||.::|...:.|          :..:|.:..::|       |:.|..|:|.....:.|.
 Frog   224 IARVEKVFLKKQVS----------QTKIRVISTILFIVAGCLVFVTIPAVIFKQIEGWTEL---- 274

  Fly   424 SFFKSIPDAFWWAVVTMTTVGYGDMTPVG-------------VWGKIVGSLCAIAGVLTIALPVP 475
                   ::.::.|||:||:|:||....|             ||..|:..|...|.||:
 Frog   275 -------ESLYFVVVTLTTIGFGDFVAGGNADISYREWYKPLVWFWILVGLAYFAAVLS------ 326

  Fly   476 VIVSNFNYFYHRETDQEEMQSQNFNHVTSCPYLPGTLGQH---MKKSSLSESSSDMMDLDDGVES 537
             ::.::.....::|.:|                .|.:..|   .|.:..:|.......|  .||.
 Frog   327 -MIGDWLRVISKKTKEE----------------VGEIKAHAAEWKANVTAEFRETRRRL--SVEI 372

  Fly   538 TPGLTETHPGRSAVAPFLGAQQQQQQPVASSLSMSIDKQLQHPLQQLTQTQLYQQQQQQQQQQQN 602
            ...|......||.....||..|:     |.||.| :..:.:....:|...:.....|.....:.|
 Frog   373 HDKLQRAATIRSMERRRLGLDQR-----AHSLDM-LSPEKRSVFAELEAGRFKASSQDSINNRPN 431

  Fly   603 G--FKQQQQQTQQQLQQQQSHTINASAAAATSGSGSSGLTMRHNNALAVSIETDV 655
            .  .|..:|.|.......:.:.||      ..||.||.||.|.|..|..::..||
 Frog   432 NLRLKGAEQFTLHGQGVSEDNIIN------KFGSNSSKLTKRKNKDLKKNLPEDV 480

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sh	NP_728123.1	BTB_POZ	97..223	CDD:453885
		Ion_trans	226..488	CDD:459842	27/141 (19%)
kcnk10	XP_002933240.1	Ion_trans_2	<160..216	CDD:462301
		Ion_trans_2	254..333	CDD:462301	21/96 (22%)