Protein Alignment Sh and kcna10

DIOPT Version :10

• Sequence 1: NP_728123.1
• Gene: Sh / 32780
• FlyBaseID: FBgn0003380
• Length: 655
• Species: Drosophila melanogaster
• Sequence 2: XP_002938481.1
• Gene: kcna10 / 100497698
• XenbaseID: XB-GENE-991589
• Length: 499
• Species: Xenopus tropicalis
• Alignment Length: 528
• Identity: 286/528 - (54%)
• Similarity: 364/528 - (68%)
• Gaps: 61/528 - (11%)

  Fly    29 EQLEQKEEQKKIAERKLQLREQQLQRNSLDGYGSLPKLSSQDEEGGAGHGFGGGPQHFEPIPHDH 93
            |..|:.|..|.::..|:.:.....|..:....|: ..|:::.|             ||......|
 Frog     9 EHPEETELHKDVSATKVAISSYVNQNLNWKAPGN-ENLNNETE-------------HFRFNSKSH 59

  Fly    94 DFC------------ERVVINVSGLRFETQLRTLNQFPDTLLGDPARRLRYFDPLRNEYFFDRSR 146
            | |            :||.||::||||||.|:||::|||||||||.:|:.|||.:||||||||:|
 Frog    60 D-CLFLELMSMEEGDQRVFINIAGLRFETHLKTLSEFPDTLLGDPKKRIHYFDSMRNEYFFDRNR 123

  Fly   147 PSFDAILYYYQSGGRLRRPVNVPLDVFSEEIKFYELGDQAINKFREDEGFIKEEERPLPDNEKQR 211
            ||||.|||||||||::|||.|||:|||::||.|||||::|:::||:||||:|:.|.|||.|:..:
 Frog   124 PSFDGILYYYQSGGKIRRPANVPIDVFADEINFYELGNEAMDQFRDDEGFLKDPEIPLPTNDYYK 188

  Fly   212 KVWLLFEYPESSQAARVVAIISVFVILLSIVIFCLETLPEFKHYK-VFNTTTNGTKIEEDEVPD- 274
            :.||||||||||.|||.:|::||.||::||:|||:||||||:..: ::.....|...|....|.
 Frog   189 QFWLLFEYPESSTAARGMALVSVLVIIISILIFCMETLPEFREERDLYFYRGTGNYSESTTHPST 253

  Fly   275 ITDPFFLIETLCIIWFTFELTVRFLACPNKLNFCRDVMNVIDIIAIIPYFITLATVVAEEEDTLN 339
            .|||||:|||.||.||:|||.|||:.||:...|.|::||:||:::|||||:||.|.:.::.:
 Frog   254 FTDPFFMIETTCIAWFSFELVVRFVVCPSTSAFFRNIMNIIDLVSIIPYFVTLVTELFKQTE--- 315

  Fly   340 LPKAPVSPQDKSSNQAMSLAILRVIRLVRVFRIFKLSRHSKGLQILGRTLKASMRELGLLIFFLF 404
                ||..|:      |||||||::||||||||||||||||||||||:|||||||||||||||||
 Frog   316 ----PVGQQN------MSLAILRIVRLVRVFRIFKLSRHSKGLQILGQTLKASMRELGLLIFFLF 370

  Fly   405 IGVVLFSSAVYFAEAGSENSFFKSIPDAFWWAVVTMTTVGYGDMTPVGVWGKIVGSLCAIAGVLT 469
            |||:||||||||||.....|.|.||||.||||||||||||||||.|:.:.||:||:|||||||||
 Frog   371 IGVILFSSAVYFAEVDEPQSQFLSIPDGFWWAVVTMTTVGYGDMCPITLSGKVVGTLCAIAGVLT 435

  Fly   470 IALPVPVIVSNFNYFYHRETDQEEMQSQNFNHVTSCPYLP--------GTLGQHMKKSSLSESSS 526
            ||||||||||||||||||||:.||..|           ||        |.|.:....|||.:::.
 Frog   436 IALPVPVIVSNFNYFYHRETENEERHS-----------LPVEVEKISLGNLIRAGSSSSLKKNNG 489

  Fly   527 DMMDLDDG 534
            ..:...:|
 Frog   490 SCVSDKNG 497

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sh	NP_728123.1	BTB_POZ	97..223	CDD:453885	85/125 (68%)
		Ion_trans	226..488	CDD:459842	170/263 (65%)
kcna10	XP_002938481.1	BTB_POZ	74..200	CDD:453885	85/125 (68%)
		Ion_trans	252..454	CDD:459842	149/214 (70%)