Protein Alignment Sh and kcng2

DIOPT Version :9

• Sequence 1: NP_001303569.1
• Gene: Sh / 32780
• FlyBaseID: FBgn0003380
• Length: 655
• Species: Drosophila melanogaster
• Sequence 2: XP_017950308.2
• Gene: kcng2 / 100497537
• XenbaseID: XB-GENE-954003
• Length: 489
• Species: Xenopus tropicalis
• Alignment Length: 440
• Identity: 136/440 - (30%)
• Similarity: 217/440 - (49%)
• Gaps: 60/440 - (13%)

  Fly    94 DFCERVVINVSGLRFETQLRTLNQFPDTLLGDPARRLRY---------FDPLRNEYFFDRSRPSF 149
            |....|:|||.|:::.....||...|.|.||.......|         :|...||:||||:..:|
 Frog    58 DRTRHVIINVGGIKYRIPWTTLENCPLTRLGKLKTCNNYDEIMDVCDDYDINCNEFFFDRNPCAF 122

  Fly   150 DAILYYYQSGGRLRRPVNVPLDVFSEEIKFYELGDQAIN-----------------KFREDEGFI 197
            ..|:.:. :.|:||....:....|.||:.::.:.::.:.                 |..|.|..|
 Frog   123 RTIMTFL-AAGKLRILREMCALSFQEELIYWGIEEEQLEWCCLRKLQQKEEELAEAKMYEGESGI 186

  Fly   198 KEE--ERPLPDNEK----QRKVWLLFEYPESSQAARVVAIISVFVILLSIVIFCLETLPEFKHYK 256
            ..|  :..|.|:.:    .:.:..:.|.|.|....::.|.:||..:.::.|..|:.|:|:|:.
 Frog   187 SNENSQSALQDSGRLAQCMKHLRDMVENPHSGIPGKIFACLSVSFVAITAVSLCISTMPDFRD-- 249

  Fly   257 VFNTTTNGTKIEED--EVPDITDPFFLIETLCIIWFTFELTVRFLACPNKLNFCRDVMNVIDIIA 319
                       |||  |........|::||:|:.||:.|..:||:...:|..|.|..:|:|||:|
 Frog   250 -----------EEDRGECSQKCYDIFVLETVCVAWFSLEFVLRFIQAESKCVFLRTPLNMIDIMA 303

  Fly   320 IIPYFITLATVVAEEEDTLNLPKAPVSPQDKSSNQAMSLAILRVIRLVRVFRIFKLSRHSKGLQI 384
            |:||:|||..      |.|:..|...:..:......:   :|||:|.:|:..:.:|:|||.|||.
 Frog   304 ILPYYITLIV------DALSGGKTGGAGNNYLEKVGL---VLRVLRALRILYVMRLARHSLGLQT 359

  Fly   385 LGRTLKASMRELGLLIFFLFIGVVLFSSAVYFA--EAGSDSSFFKSIPDGFWWAVVTMTTVGYGD 447
            ||.|::...||.|||:.||.:.:.|||..||.|  |.|:... |.|||..:||||::||||||||
 Frog   360 LGLTVRRCTREFGLLLLFLCVAMALFSPLVYLAENELGAKQE-FTSIPGSYWWAVISMTTVGYGD 423

  Fly   448 MRPVGVWGKIVGSLCAIAGVLTIALPVPVIVSNFNYFYHRETDQEEMQSQ 497
            |.|..:.|::|.....::|:|.:|.||..|...|:..|....:|::..|:
 Frog   424 MVPRSIPGQVVALSSILSGILLMAFPVTSIFHTFSRSYTELKEQQQRASR 473

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sh	NP_001303569.1	BTB_2	99..187	CDD:280393	27/96 (28%)
		BTB	99..182	CDD:197585	27/91 (30%)
		Ion_trans	274..488	CDD:278921	84/215 (39%)
		Ion_trans_2	403..479	CDD:285168	35/77 (45%)
kcng2	XP_017950308.2	BTB_POZ_KCNG1_2	58..171	CDD:349728	28/113 (25%)
		Ion_trans	222..465	CDD:395416	96/265 (36%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000074
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X19
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.000