Protein Alignment Sh and kcnb1

DIOPT Version :9

• Sequence 1: NP_001303569.1
• Gene: Sh / 32780
• FlyBaseID: FBgn0003380
• Length: 655
• Species: Drosophila melanogaster
• Sequence 2: XP_031750650.1
• Gene: kcnb1 / 100489405
• XenbaseID: XB-GENE-982937
• Length: 875
• Species: Xenopus tropicalis
• Alignment Length: 589
• Identity: 194/589 - (32%)
• Similarity: 298/589 - (50%)
• Gaps: 125/589 - (21%)

  Fly    98 RVVINVSGLRFETQLRTLNQFPDTLLGDPARRLR-------------YFDPLRNEYFFDRSRPSF 149
            ||.:||.||..|...|||::.|.|.||    :||             .::...|||||||...:|
 Frog    32 RVKLNVGGLAHEVLWRTLDRLPRTRLG----KLRDCNTHECLMEICDDYNLEENEYFFDRHPGAF 92

  Fly   150 DAILYYYQSGGRLRRPVNVPLDVFSEEI----------------KFYELGDQAINKFREDEGFIK 198
            .:||.:|:: |:|.....:....||:|:                ::::..:|...:.:.:...::
 Frog    93 TSILNFYRT-GKLHMMEEMCALSFSQELDYWGIDEIYLESCCQARYHQKKEQMNEELKREAETLR 156

  Fly   199 EEERPLPDN----EKQRKVWLLFEYPESSQAARVVAIISVFVILLSIVIFCLETLPEFKHYKVFN 259
            |.|....||    :|::|:|.|.|.|.||.||:::||||:..|:||.:...|.|||:.:....|.
 Frog   157 EREGEEFDNTCCADKRKKLWDLLEKPNSSVAAKILAIISILFIVLSTIALSLNTLPDLQGIDEFG 221

  Fly   260 TTTNGTKIEEDEVPDITDPFFLIETLCIIWFTFELTVRFLACPNKLNFCRDVMNVIDIIAIIPYF 324
            .||:..::..            :|.:||.|||.|..:|||:.|||..|.:..:||||::||:||:
 Frog   222 QTTDNPQLAH------------VEAVCIAWFTMEYLLRFLSSPNKWKFFKGPLNVIDLLAILPYY 274

  Fly   325 ITLATVVAEEEDTLNLPKAPVSPQDKSSNQAMSL-AILRVIRLVRVFRIFKLSRHSKGLQILGRT 388
            :|:.                ::..:||..|..:: .::::.|::|:.||.||:|||.|||.||.|
 Frog   275 VTIF----------------LTESNKSVLQFQNVRRVVQIFRIMRILRILKLARHSTGLQSLGFT 323

  Fly   389 LKASMRELGLLIFFLFIGVVLFSSAVYFAEAGSDSSFFKSIPDGFWWAVVTMTTVGYGDMRPVGV 453
            |:.|..||||||.||.:|:::|||.|:|||...:.:.|||||..||||.:|||||||||:.|..:
 Frog   324 LRRSYNELGLLILFLAMGIMIFSSLVFFAEKDEEDTKFKSIPASFWWATITMTTVGYGDIYPKTL 388

  Fly   454 WGKIVGSLCAIAGVLTIALPVPVIVSNFNYFYHRETDQE---------EMQSQNFNHVTSCPYLP 509
            .|||||.||.|||||.||||:|:||:||:.||..:..||         |...:|.:.|:
 Frog   389 LGKIVGGLCCIAGVLVIALPIPIIVNNFSEFYKEQKRQEKAIKRREALERAKRNGSIVS------ 447

  Fly   510 GTLGQHMKKSSLSESSSDMMDL-----------DDGVES---TPG--------LTETHPGRSAVA 552
                  |........|.::||:           .|.|:.   :|.        |:||...:|..|
 Frog   448 ------MNMKDAFARSVELMDVVVEKTDDNSGRKDKVQDNHLSPSRWKWTKRTLSETSSNKSFDA 506

  Fly   553 PFLGAQQQQQQPVASSLSMSIDKQLQH-PLQQLTQTQLYQQQQQQQQQQQNGFKQQQQQTQ--QQ 614
                  ::|..|..:..|.|    .|| .:|||  ..:|.:..:.|.|.....|...|.::  ::
 Frog   507 ------KEQGSPEKARCSSS----PQHLNVQQL--EDIYNKMAKTQSQPVLNSKDSNQPSKPAEE 559

  Fly   615 LQQQ 618
            |:.:
 Frog   560 LEME 563

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sh	NP_001303569.1	BTB_2	99..187	CDD:280393	32/116 (28%)
		BTB	99..182	CDD:197585	31/111 (28%)
		Ion_trans	274..488	CDD:278921	101/214 (47%)
		Ion_trans_2	403..479	CDD:285168	46/75 (61%)
kcnb1	XP_031750650.1	BTB_POZ_KCNB2	15..141	CDD:349719	32/113 (28%)
		Ion_trans	188..424	CDD:395416	116/263 (44%)
		Kv2channel	467..720	CDD:397541	23/109 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X19
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.000