Protein Alignment Sh and kcnd1

DIOPT Version :9

• Sequence 1: NP_001303569.1
• Gene: Sh / 32780
• FlyBaseID: FBgn0003380
• Length: 655
• Species: Drosophila melanogaster
• Sequence 2: XP_031747765.1
• Gene: kcnd1 / 100488387
• XenbaseID: XB-GENE-6047565
• Length: 631
• Species: Xenopus tropicalis
• Alignment Length: 594
• Identity: 183/594 - (30%)
• Similarity: 294/594 - (49%)
• Gaps: 129/594 - (21%)

  Fly    97 ERVVINVSGLRFETQLRTLNQFPDTLLGDPARRLRYFDPLRNEYFFDRSRPSFDAILYYYQSGGR 161
            |.:|:||||.:|:|...||:::||||||...:.. :|:....||||||....|..||.:|:: |:
 Frog    40 EILVVNVSGRKFQTWKNTLDRYPDTLLGSTEKDF-FFNQDTQEYFFDRDPEMFRHILNFYRT-GK 102

  Fly   162 LRRPVNVPLDVFSEEIKFYE-----LGDQAINKFR-----------EDEGFIKEEERPL-PDNEK 209
            |..|.:..:..|.||:.||.     :||..:.::|           ||.......:.|| ||:..
 Frog   103 LHYPRHECIQAFDEELSFYGIIPEIIGDCCLEEYRDRKKENLERLAEDTEAETAGDTPLPPDSTF 167

  Fly   210 QRKVWLLFEYPESSQAARVVAIISVFVILLSIVIFCLETLP---------EFKHYKVFNTTTNGT 265
            ::::|..||.|.:|..|.|...::.|.|.:|::...:||:|         |....:.:|..
 Frog   168 RQRLWRAFENPHTSTMALVFYYVTGFFIAVSVIANVVETVPCRPPAGRLKELPCGEKYNLA---- 228

  Fly   266 KIEEDEVPDITDPFFLIETLCIIWFTFELTVRFLACPNKLNFCRDVMNVIDIIAIIPYFITLATV 330
                         |..::|.|::.||||..:|..|.|::..|.|.||::||::||:|::|.|
 Frog   229 -------------FVCMDTACVLIFTFEYLMRLFAAPSRCKFMRSVMSIIDVVAIMPFYIGL--- 277

  Fly   331 VAEEEDTLNLPKAPVSPQDKSSNQAMSLAILRVIRLVRVFRIFKLSRHSKGLQILGRTLKASMRE 395
                          |.|:    |:.:|.|.: .:|:.|||||||.||||:||:|||.|||:...|
 Frog   278 --------------VMPE----NENVSGAFV-TLRVFRVFRIFKFSRHSQGLRILGYTLKSCASE 323

  Fly   396 LGLLIFFLFIGVVLFSSAVYFAEAGSDSSFFKSIPDGFWWAVVTMTTVGYGDMRPVGVWGKIVGS 460
            ||.|:|.|.:.:::|::.:::||.|:..:.|.|||..||:.:|||||:|||||.|..:.|||.||
 Frog   324 LGFLLFSLTMAIIIFATVMFYAEKGTSKTKFTSIPAAFWYTIVTMTTLGYGDMVPDTIAGKIFGS 388

  Fly   461 LCAIAGVLTIALPVPVIVSNFNYFYHRETDQEEMQSQNFNHVTSCPYL-PGTLGQHMKKSSLSES 524
            :|:::|||.||||||||||||:..||:....::.::|....:...... ..|.|..::   ..||
 Frog   389 ICSLSGVLVIALPVPVIVSNFSRIYHQNQRADKRRAQQKIRLARIRLAKSNTTGAFLR---YKES 450

  Fly   525 SSDMMDLDDGVESTPGLTETH----PGRSAVAPFLGAQQQQQQPVASSLSMSIDKQLQHPLQQLT 585
            ..    |::|       ||:|    ..|||                      .:.|..|.|..|.
 Frog   451 GG----LEEG-------TESHALCVKNRSA----------------------FELQHHHLLHCLE 482

  Fly   586 QTQLYQQQQQQQQQQQNGFKQQQQQTQQQLQQQQSH-TINASAAAATSGSGSSGLTMRH------ 643
            :|..::            |..|...::..:.:...: |..:::.::..|.|:|....|:
 Frog   483 KTTCHE------------FTDQHTYSEALMTESIGYRTSRSTSVSSQQGFGTSCCPRRNKRRAIR 535

  Fly   644 --NNALAVS 650
              |:.::||
 Frog   536 LANSTVSVS 544

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sh	NP_001303569.1	BTB_2	99..187	CDD:280393	36/92 (39%)
		BTB	99..182	CDD:197585	34/87 (39%)
		Ion_trans	274..488	CDD:278921	96/213 (45%)
		Ion_trans_2	403..479	CDD:285168	39/75 (52%)
kcnd1	XP_031747765.1	BTB_POZ_KCND1	6..143	CDD:349724	38/104 (37%)
		Ion_trans	184..415	CDD:395416	105/269 (39%)
		DUF3399	445..542	CDD:403174	23/144 (16%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X19
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.000