Protein Alignment Sh and LOC100332207

DIOPT Version :9

• Sequence 1: NP_001303569.1
• Gene: Sh / 32780
• FlyBaseID: FBgn0003380
• Length: 655
• Species: Drosophila melanogaster
• Sequence 2: XP_005171693.2
• Gene: LOC100332207 / 100332207
• -ID: -
• Length: 534
• Species: Danio rerio
• Alignment Length: 567
• Identity: 296/567 - (52%)
• Similarity: 373/567 - (65%)
• Gaps: 70/567 - (12%)

  Fly     9 GLGEDRQHRKKQQQQQQHQKEQLEQKEEQKKIAERKLQLREQQLQRNSLDGYGSLPKLSSQDEEG 73
            |.||:..:.|.:.:.|..:    |..|..||:.:          |||..: .|...|...:.|..
Zfish     4 GEGEEESNSKMEDKTQTEE----EVSESDKKLKD----------QRNKAE-KGDKEKGEKKRENR 53

  Fly    74 GAGHGFGGGPQHFEPIPHDHDFCERVVINVSGLRFETQLRTLNQFPDTLLGDPARRLRYFDPLRN 138
            .:|..:.||          ....||:.|||||:|:|||:|||.||||:|||||.|||||||||||
Zfish    54 RSGSTWRGG----------WALSERLAINVSGMRYETQIRTLAQFPDSLLGDPRRRLRYFDPLRN 108

  Fly   139 EYFFDRSRPSFDAILYYYQSGGRLRRPVNVPLDVFSEEIKFYELGDQAINKFREDEGFIKEEERP 203
            |.|.||:|..||||||:||||||||||.|||||||.:|::|||||:..:.:|:|||||.|||.||
Zfish   109 EIFLDRNRFCFDAILYFYQSGGRLRRPANVPLDVFMDELRFYELGEDIMARFKEDEGFPKEEPRP 173

  Fly   204 LPDNEKQRKVWLLFEYPESSQAARVVAIISVFVILLSIVIFCLETLPEFK---------HYKVFN 259
            ||::|.|||:|:|||:||||..||::|||||.||::||:||||||||:|:         .|:...
Zfish   174 LPESEFQRKIWMLFEHPESSGGARIIAIISVMVIVVSILIFCLETLPDFRVEKEQREKMAYEAHL 238

  Fly   260 TTTNGTKIEEDEVPDITDPFFLIETLCIIWFTFELTVRFLACPNKLNFCRDVMNVIDIIAIIPYF 324
            ...|.:.|....  ...|||||:||:||.||:|||.:||...|||:.|.:||||:||..||||||
Zfish   239 AGNNTSHISMSS--PFHDPFFLVETMCICWFSFELIMRFTCSPNKMVFFKDVMNIIDFFAIIPYF 301

  Fly   325 ITLATVVAEEEDTLNLPKAPVSPQDKSSNQAMSLAILRVIRLVRVFRIFKLSRHSKGLQILGRTL 389
            :||.|.:|               :.|.:..:|||||:|||||||||||||||||||||||||:||
Zfish   302 VTLGTELA---------------KSKGATPSMSLAIVRVIRLVRVFRIFKLSRHSKGLQILGQTL 351

  Fly   390 KASMRELGLLIFFLFIGVVLFSSAVYFAEAGSDSSFFKSIPDGFWWAVVTMTTVGYGDMRPVGVW 454
            |||:|||.||||||||||:|||||.||||..:..:.|.|||:.||||||:|||||||||.||.|.
Zfish   352 KASLRELALLIFFLFIGVILFSSAAYFAEVDNPETAFTSIPEAFWWAVVSMTTVGYGDMYPVTVG 416

  Fly   455 GKIVGSLCAIAGVLTIALPVPVIVSNFNYFYHRETDQEEMQSQNFNHVTSCPYLP----GTLGQH 515
            ||:|||:|||||||||:||||||||||:||||||.:.|:  :|.:.||::..:..    |..|::
Zfish   417 GKLVGSMCAIAGVLTISLPVPVIVSNFSYFYHREMECED--NQEYTHVSTSLWEEEEEGGEDGEN 479

  Fly   516 MKKSSLSESSSDMMDLDDGV----ESTP-------GLTETHPGRSAV 551
            .::.  .....|.:.|:.|.    ..||       ||....||..:|
Zfish   480 GEEG--PGEQGDQVPLEGGTAYRGNCTPLNGTLLAGLCSGKPGEQSV 524

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sh	NP_001303569.1	BTB_2	99..187	CDD:280393	66/87 (76%)
		BTB	99..182	CDD:197585	63/82 (77%)
		Ion_trans	274..488	CDD:278921	144/213 (68%)
		Ion_trans_2	403..479	CDD:285168	56/75 (75%)
LOC100332207	XP_005171693.2	BTB_2	71..160	CDD:308049	66/88 (75%)
		Ion_trans	196..451	CDD:306908	168/271 (62%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D307298at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	1.010