Protein Alignment Sh and LOC100330283

DIOPT Version :10

• Sequence 1: NP_728123.1
• Gene: Sh / 32780
• FlyBaseID: FBgn0003380
• Length: 655
• Species: Drosophila melanogaster
• Sequence 2: XP_005174156.1
• Gene: LOC100330283 / 100330283
• -ID: -
• Length: 515
• Species: Danio rerio
• Alignment Length: 490
• Identity: 325/490 - (66%)
• Similarity: 381/490 - (77%)
• Gaps: 47/490 - (9%)

  Fly    55 NSLDGYGSLPKLSSQDEEGGAGHGFGGGPQHFEPIPHDHDFCERVVINVSGLRFETQLRTLNQFP 119
            |.|:...:||           ||   ...:.:||   ||:.|||||||:|||||||||:||:|||
Zfish    41 NMLEESAALP-----------GH---HSLERYEP---DHECCERVVINISGLRFETQLKTLSQFP 88

  Fly   120 DTLLGDPARRLRYFDPLRNEYFFDRSRPSFDAILYYYQSGGRLRRPVNVPLDVFSEEIKFYELGD 184
            :||||||.:|:||||||||||||||:||||||||||||||||:|||||||:|:|||||:|||||:
Zfish    89 ETLLGDPKKRMRYFDPLRNEYFFDRNRPSFDAILYYYQSGGRIRRPVNVPIDIFSEEIRFYELGE 153

  Fly   185 QAINKFREDEGFIKEEERPLPDNEKQRKVWLLFEYPESSQAARVVAIISVFVILLSIVIFCLETL 249
            :|:.|||||||||||||||||.||.||:|||||||||||..||.:||:||.|||:||||||||||
Zfish   154 EAMEKFREDEGFIKEEERPLPTNEFQRQVWLLFEYPESSGPARGIAIVSVLVILISIVIFCLETL 218

  Fly   250 PEFKHYKVFNT---TTNGTKIEEDEVPDIT----DPFFLIETLCIIWFTFELTVRFLACPNKLNF 307
            |||:. .:.:|   ..|||      :|.:|    ||||::||||||||:|||.|||.|||:|..|
Zfish   219 PEFRD-DIDSTVAPVVNGT------IPYLTSPFSDPFFVVETLCIIWFSFELLVRFFACPSKATF 276

  Fly   308 CRDVMNVIDIIAIIPYFITLATVVAEEEDTLNLPKAPVSPQDKSSNQAMSLAILRVIRLVRVFRI 372
            .:::||:|||:|||||||||.|.:||.:.              :..|||||||||||||||||||
Zfish   277 SKNIMNIIDIVAIIPYFITLGTELAERQG--------------NGQQAMSLAILRVIRLVRVFRI 327

  Fly   373 FKLSRHSKGLQILGRTLKASMRELGLLIFFLFIGVVLFSSAVYFAEAGSENSFFKSIPDAFWWAV 437
            ||||||||||||||:||||||||||||||||||||:|||||||||||...:|.|.||||||||||
Zfish   328 FKLSRHSKGLQILGQTLKASMRELGLLIFFLFIGVILFSSAVYFAEADDPDSGFNSIPDAFWWAV 392

  Fly   438 VTMTTVGYGDMTPVGVWGKIVGSLCAIAGVLTIALPVPVIVSNFNYFYHRETDQEEMQSQNFNHV 502
            |||||||||||.||.:.|||||||||||||||||||||||||||||||||||:.|| |:| :.|:
Zfish   393 VTMTTVGYGDMHPVTIGGKIVGSLCAIAGVLTIALPVPVIVSNFNYFYHRETEGEE-QAQ-YLHI 455

  Fly   503 TSCPYLPGTLGQHMKKSSLSESSSDMMDLDDGVES 537
            .|...|..:......:|:.|.|.|:.|.:::|:.|
Zfish   456 GSLQPLSSSGELKKTRSTSSVSKSEYMVIEEGINS 490

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sh	NP_728123.1	BTB_POZ	97..223	CDD:453885	106/125 (85%)
		Ion_trans	226..488	CDD:459842	189/268 (71%)
LOC100330283	XP_005174156.1	BTB_POZ	66..192	CDD:453885	106/125 (85%)
		Ion_trans	195..443	CDD:459842	189/268 (71%)