Protein Alignment Sh and kcnk6

DIOPT Version :10

• Sequence 1: NP_728123.1
• Gene: Sh / 32780
• FlyBaseID: FBgn0003380
• Length: 655
• Species: Drosophila melanogaster
• Sequence 2: NP_001120420.1
• Gene: kcnk6 / 100145504
• XenbaseID: XB-GENE-958681
• Length: 308
• Species: Xenopus tropicalis
• Alignment Length: 377
• Identity: 77/377 - (20%)
• Similarity: 135/377 - (35%)
• Gaps: 109/377 - (28%)

  Fly   212 KVWLLFEYPESSQAARVVAIISVFVILLSIVIFCLETLPEFKHYKVFNTTTNGTKIEEDEVPDIT 276
            |.|||.        ..:|....::::|.::||..:|:..|..              ..||:..:.
 Frog     2 KFWLLL--------TLLVCAYVIYLLLGALVISVIESPYEAS--------------LRDELRQLK 44

  Fly   277 DPFFLIETLCIIWFTFELTVRFLACPNKL------NFCRDVMNVIDIIAIIPYFITLATVVAEEE 335
            . .||.|:.|:...:.|..:..:...||.      |...|  :..||.:.:.:..||.|.|....
 Frog    45 S-VFLNESPCVNVSSLEAFLEKIINANKYGVSVLHNASND--SKWDIASSMFFASTLVTTVGYGY 106

  Fly   336 DTLNLPKAPVSPQDKS-----------------SNQAMSLAIL---RVIRLVRVFRIFK----LS 376
            .|      |::...|:                 |:....|.::   :.|..::|.|.|.    ..
 Frog   107 TT------PLTDSGKAFCIFYALIGVPFTMLVLSSFVQRLMVMFTHKPIHYLQVQRGFDRKMVTQ 165

  Fly   377 RHSKGLQILGRTLKASMRELGLLIFFLFIGVVLFSSAVYFAEAGSENSFFKSIPDAFWWAVVTMT 441
            .|...|.||            :|:|||.|...:|::.        |.::  |..|||::..:::.
 Frog   166 LHFFFLLIL------------VLVFFLIIPSAIFNTI--------ETTW--SFLDAFYFCFISLC 208

  Fly   442 TVGYGDMTP---VGVW----GKIVGSLCAIAGVLTIALPVPVIVSNFNYFYHRETDQEEMQSQNF 499
            |:|.||..|   ...|    .|:..:.....|::.:.|    ||..|    |:..|        .
 Frog   209 TIGLGDYVPGEQNDQWLRKLYKVSVAFYLFIGLMAMLL----IVQTF----HKAAD--------L 257

  Fly   500 NHVTSCPYLPGTLGQHMKKSSLSESSSDMMDLDDGVESTPGLTETHPGRSAV 551
            :.:|...|||....|..::..|..:.....||:   ...|..:|:.|..|::
 Frog   258 HGLTDIFYLPRLQDQDDQEPILETTDYSTRDLE---PKRPLASESQPDYSSI 306

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sh	NP_728123.1	BTB_POZ	97..223	CDD:453885	4/10 (40%)
		Ion_trans	226..488	CDD:459842	60/298 (20%)
kcnk6	NP_001120420.1	Ion_trans_2	76..141	CDD:462301	12/72 (17%)
		Ion_trans_2	<194..251	CDD:462301	15/62 (24%)