Protein Alignment CG6847 and LIPG

DIOPT Version :10

• Sequence 1: NP_573259.2
• Gene: CG6847 / 32778
• FlyBaseID: FBgn0030884
• Length: 1000
• Species: Drosophila melanogaster
• Sequence 2: NP_006024.1
• Gene: LIPG / 9388
• HGNCID: 6623
• Length: 500
• Species: Homo sapiens
• Alignment Length: 487
• Identity: 138/487 - (28%)
• Similarity: 203/487 - (41%)
• Gaps: 130/487 - (26%)

  Fly    72 VCYGELGCFEDSGPFAYLEMLPSSPE-EINTKFYFYSTRQRSDRPLMELSFLNMTNAFRGKRETE 135
            :||    ||....|      :|..|| .:..|.:.....|...:|.:..:..
Human    13 LCY----CFAAGSP------VPFGPEGRLEDKLHKPKATQTEVKPSVRFNLR------------- 54

  Fly   136 VSTSSPEGTSGRSSVA-SAPSSMSAVNATTFTTERPGGGQKKPTPSIDDLEGFDELSVRVIVHGF 199
             ::..||......||. |.|....:.|.|..|.                          .|:||:
Human    55 -TSKDPEHEGCYLSVGHSQPLEDCSFNMTAKTF--------------------------FIIHGW 92

  Fly   200 G-SACPHVWIYEMKTALMAVE-DCIVICVDWENGATFP----NYVRAAANTRLVGKQLAMLLRNL 258
            . |.....|::::.:||...| |..|:.|||     .|    .|..|..|||:||..:|.:|..|
Human    93 TMSGIFENWLHKLVSALHTREKDANVVVVDW-----LPLAHQLYTDAVNNTRVVGHSIARMLDWL 152

  Fly   259 QQHKGLDLMRTHVIGFSLGAHVSGFAGAELPG-LSRITGLDPAGPLFEAQHPKVRLDSSDAEFVD 322
            |:.....|...|:||:||||||:|:||..:.| :.||||||||||:||......||...||:|||
Human   153 QEKDDFSLGNVHLIGYSLGAHVAGYAGNFVKGTVGRITGLDPAGPMFEGADIHKRLSPDDADFVD 217

  Fly   323 VIHSNGENLILGGLGSWQPMGHVDYYPNGGRVQTGC------SNLFVGAVTDFIWSAQAAEDEEG 381
            |:|:...:..| .:|...|:||:|.|||||..|.||      .::..|.:|:.:
Human   218 VLHTYTRSFGL-SIGIQMPVGHIDIYPNGGDFQPGCGLNDVLGSIAYGTITEVV----------- 270

  Fly   382 RSLCNHRRAYKFFIDSVA--PRCLFPAFPCGNYDDFLKGRCFPCAQDDEDLAEGVPRCGNMGYYA 444
              .|.|.||...|:||:.  .:..| ||.|.:.:.|.||.|..|.::         ||.::||.|
Human   271 --KCEHERAVHLFVDSLVNQDKPSF-AFQCTDSNRFKKGICLSCRKN---------RCNSIGYNA 323

  Fly   445 D--RSTGRGQLYLLTREEEPFCAHQFQLQI--FNSFN--------------------DLPLRTIG 485
            .  |:....::||.||...||..:.:|::|  |:..|                    .|||..:.
Human   324 KKMRNKRNSKMYLKTRAGMPFRVYHYQMKIHVFSYKNMGEIEPTFYVTLYGTNADSQTLPLEIVE 388

  Fly   486 RLEAILEGDGGLNETFEISEKDDAEFFAGDIV 517
            |:|.      ....||.:..::|    .||::
Human   389 RIEQ------NATNTFLVYTEED----LGDLL 410

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6847	NP_573259.2	Pancreat_lipase_like	185..459	CDD:238363	101/290 (35%)
LIPG	NP_006024.1	lipo_lipase	50..485	CDD:132274	127/440 (29%)