Protein Alignment CG6847 and Pla1a

DIOPT Version :10

• Sequence 1: NP_573259.2
• Gene: CG6847 / 32778
• FlyBaseID: FBgn0030884
• Length: 1000
• Species: Drosophila melanogaster
• Sequence 2: NP_598863.3
• Gene: Pla1a / 85031
• MGIID: 1934677
• Length: 456
• Species: Mus musculus
• Alignment Length: 517
• Identity: 139/517 - (26%)
• Similarity: 199/517 - (38%)
• Gaps: 130/517 - (25%)

  Fly   115 PLMELSFLNMTNAFRGKRETEVSTSSPEGTSGRSSVASAPSSMSAVNATTFTTERPGGGQKKPTP 179
            ||:.||.        |.......|:.|:.|..:|:.....:::. |....||...|..||...
Mouse    15 PLLWLSI--------GSSGNVPPTTQPKCTDFQSANLLRGTNLK-VQFLLFTPSDPSCGQLVE-- 68

  Fly   180 SIDDLEGFD--------ELSVRVIVHGFGS-ACPHVWIYEMKTALMAVEDCIVICVDWENGATFP 235
                 ||.|        .|..:||:|||.: .....||.:..:|::...|..||.|||..|:| .
Mouse    69 -----EGSDIRSSEFNASLGTKVIIHGFRALGTKPSWIDKFISAVLRAADANVIAVDWVYGST-G 127

  Fly   236 NYVRAAANTRLVGKQLAMLLRNLQQHKGLDLMRTHVIGFSLGAHVSGFAGAELPG-LSRITGLDP 299
            .|..|..|...:..:::..|..|.: .|:.....|:||.||||||.|..|....| |.:||||||
Mouse   128 VYYSAVENVVKLSLEISRFLSKLLE-LGVSESSIHIIGVSLGAHVGGMVGHFYKGQLGQITGLDP 191

  Fly   300 AGPLFEAQHPKVRLDSSDAEFVDVIHSNGENLILGGLGSWQPMGHVDYYPNGGRVQTGCSNLFVG 364
            |||.:.....:.|||:.||.||:.||::.:|     ||...|:|||||:.|||:.|.||...|..
Mouse   192 AGPEYTRASLEERLDAGDALFVEAIHTDTDN-----LGIRIPVGHVDYFVNGGQDQPGCPAFFHA 251

  Fly   365 AVTDFIWSAQAAEDEEGRSLCNHRRAYKFFIDSVAPRCLFPAFPCGNYDDFLKGRCFPCAQDDED 429
            .....|              |:|.||...:|.::...|...||||.:|..||.|.|..|.   ..
Mouse   252 GYNYLI--------------CDHMRAVHLYISALENTCPLMAFPCASYKAFLAGDCLDCF---NP 299

  Fly   430 LAEGVPRCGNM---GYYADRSTGRGQLYLLTREEEPFCAHQFQLQIFNSFNDLPLRTIGRLEAIL 491
            .....||.|.:   |...:......::||||....|:|.|...::.:
Mouse   300 FLLSCPRIGLVERGGVMIEPLPKEVKVYLLTTSSAPYCVHHSLVEFY------------------ 346

  Fly   492 EGDGGLNETFEISEKDDAEFFAGDIVS--KIIVP-----------HP---------ALGFPTTLS 534
                 |.|..:.....:..|.:.::.|  ||.:|           ||         .|.|..:..
Mouse   347 -----LKEKRKKDTSIEVTFLSNNVTSSVKITIPKQQLEGRGVMAHPNPQCQINQVKLKFQVSSR 406

  Fly   535 LHYKSYSGWLSKGLPHWDIDKVVLTDSF--------GRSHSLCRPSTKLSSGSPVRLRLQAG 588
            :               |..|:..:..:|        ....::|.|       .||  |||||
Mouse   407 V---------------WRKDRTPVVGTFCTAPLPVNDSKKTVCIP-------EPV--RLQAG 444

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6847	NP_573259.2	Pancreat_lipase_like	185..459	CDD:238363	98/286 (34%)
Pla1a	NP_598863.3	Lipase	14..336	CDD:395099	113/360 (31%)