DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6847 and Pnliprp1

DIOPT Version :9

Sequence 1:	NP_001285397.1	Gene:	CG6847 / 32778	FlyBaseID:	FBgn0030884	Length:	1000	Species:	Drosophila melanogaster
Sequence 2:	NP_114470.1	Gene:	Pnliprp1 / 84028	RGDID:	620792	Length:	473	Species:	Rattus norvegicus

Alignment Length:	473	Identity:	151/473 - (31%)
Similarity:	220/473 - (46%)	Gaps:	103/473 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    70 KRVCYGELGCFEDSGPFA-----YLEMLPSSPEEINTKFYFYSTRQRSDRPLMELSFLNMTNAFR 129
            |.|||..||||.|:.|:|     .|::||.|||:|||:|..|:    ::.|          .||:
  Rat    18 KEVCYDNLGCFSDAEPWAGTAIRPLKLLPWSPEKINTRFLLYT----NENP----------TAFQ 68

  Fly   130 GKRETEVSTSSPEGTSGRSSVASAPSSMSAVNATTFTTERPGGGQKKPTPSIDDLEGFDELSVRV 194
                 .:..|.|                ..:.|:.|...|                     ..|.
  Rat    69 -----TLQLSDP----------------LTIGASNFQVAR---------------------KTRF 91

  Fly   195 IVHGFGSACPHVWIYEMKTALMAVEDCIVICVDWENGATFPNYVRAAANTRLVGKQLAMLLRNLQ 259
            |:|||.......|:.:|...:..||:...|||||:.|:. ..|.:||.|.|:||.|:|.::..|.
  Rat    92 IIHGFIDKGEENWVVDMCKNMFQVEEVNCICVDWKKGSQ-TTYTQAANNVRVVGAQVAQMIDILV 155

  Fly   260 QHKGLDLMRTHVIGFSLGAHVSGFAGAELPGLSRITGLDPAGPLFEAQHPKVRLDSSDAEFVDVI 324
            ::......:.|:||.||||||:|.||:..|||.|||||||....||....:||||.|||:|||||
  Rat   156 KNYSYSPSKVHLIGHSLGAHVAGEAGSRTPGLGRITGLDPVEANFEGTPEEVRLDPSDADFVDVI 220

  Fly   325 HSNGENLI-LGGLGSWQPMGHVDYYPNGGRVQTGCSNLFVGAVTDF--IWSAQAAEDEEGRSL-- 384
            |::...|| ..|.|:.|..||:|::||||:...||....:..:.|.  |||..       |..
  Rat   221 HTDAAPLIPFLGFGTNQMSGHLDFFPNGGQSMPGCKKNALSQIVDIDGIWSGT-------RDFVA 278

  Fly   385 CNHRRAYKFFIDSVAPRCLFPAFPCGNYDDFLKGRCFPCAQDDEDLAEGVPRCGNMGYYADRSTG 449
            |||.|:||::::|:.....|.|:||.:|.||...:||||....         |..||:|||:..|
  Rat   279 CNHLRSYKYYLESILNPDGFAAYPCASYKDFESNKCFPCPDQG---------CPQMGHYADKFAG 334

  Fly   450 RG-----QLYLLTREEEPFCAHQFQLQIFNSFNDLPLRTIGRLEAILEGDGGLNETFEI------ 503
            :.     :.:|.|.|.:.|...::::.:..|..    ...|:::..|.|..|....::|
  Rat   335 KSGDEPQKFFLNTGEAKNFARWRYRVSLILSGR----MVTGQVKVALFGSKGNTRQYDIFRGIIK 395

  Fly   504 -----SEKDDAEFFAGDI 516
                 |.:.||:...|.|
  Rat   396 PGATHSSEFDAKLDVGTI 413

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6847	NP_001285397.1	Lipase	70..463	CDD:278576	139/407 (34%)
CG6847	NP_001285397.1	Pancreat_lipase_like	185..459	CDD:238363	108/283 (38%)
Pnliprp1	NP_114470.1	Lipase	18..353	CDD:395099	139/407 (34%)
Pnliprp1	NP_114470.1	PLAT_PL	356..467	CDD:238857	11/62 (18%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166338904
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_28N19
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D247005at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11610
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X699
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	7	6.850