Protein Alignment CG6847 and PNLIPRP2

DIOPT Version :10

• Sequence 1: NP_573259.2
• Gene: CG6847 / 32778
• FlyBaseID: FBgn0030884
• Length: 1000
• Species: Drosophila melanogaster
• Sequence 2: NP_005387.3
• Gene: PNLIPRP2 / 5408
• HGNCID: 9157
• Length: 469
• Species: Homo sapiens
• Alignment Length: 472
• Identity: 154/472 - (32%)
• Similarity: 223/472 - (47%)
• Gaps: 99/472 - (20%)

  Fly    70 KRVCYGELGCFEDSGPFA-----YLEMLPSSPEEINTKFYFYSTRQRSDRPLMELSFLNMTNAFR 129
            |.||||:||||.|..|:|     .:::||.|||:|:|:|..|:    ::.|          |.|:
Human    18 KEVCYGQLGCFSDEKPWAGTLQRPVKLLPWSPEDIDTRFLLYT----NENP----------NNFQ 68

  Fly   130 GKRETEVSTSSPEGTSGRSSVASAPSSMSAVNATTFTTERPGGGQKKPTPSIDDLEGFDELSVRV 194
            ....||..|                     :.|:.|..:|                     ..|.
Human    69 LITGTEPDT---------------------IEASNFQLDR---------------------KTRF 91

  Fly   195 IVHGFGSACPHVWIYEMKTALMAVEDCIVICVDWENGATFPNYVRAAANTRLVGKQLAMLLRNLQ 259
            |:|||.......|..:|...:..||....|||||.:|:. ..|.:|..|.|:||.:.|.|::.|.
Human    92 IIHGFLDKAEDSWPSDMCKKMFEVEKVNCICVDWRHGSR-AMYTQAVQNIRVVGAETAFLIQALS 155

  Fly   260 QHKGLDLMRTHVIGFSLGAHVSGFAGAELPG-LSRITGLDPAGPLFEAQHPKVRLDSSDAEFVDV 323
            ...|..|...||||.|||||.:..||..|.| :.||||||||||.|:.:..:||||.|||.||||
Human   156 TQLGYSLEDVHVIGHSLGAHTAAEAGRRLGGRVGRITGLDPAGPCFQDEPEEVRLDPSDAVFVDV 220

  Fly   324 IHSNGENLILG-GLGSWQPMGHVDYYPNGGRVQTGCSNLFVGAVTDF--IWSAQAAEDEEGRSLC 385
            ||::...::.. |.|..|.:||:|::||||:...||....:..:||.  ||     |...|...|
Human   221 IHTDSSPIVPSLGFGMSQKVGHLDFFPNGGKEMPGCKKNVLSTITDIDGIW-----EGIGGFVSC 280

  Fly   386 NHRRAYKFFIDSVAPRCLFPAFPCGNYDDFLKGRCFPCAQDDEDLAEGVPRCGNMGYYADRSTGR 450
            ||.|:::::..||.....|..:||.:||:|.:.:||||.      |||.|:   ||:|||:..|:
Human   281 NHLRSFEYYSSSVLNPDGFLGYPCASYDEFQESKCFPCP------AEGCPK---MGHYADQFKGK 336

  Fly   451 GQ-----LYLLTREEEPFCAHQFQLQIFNSFNDLPLRTIGRLEAILEGDGGLNETFEI---SEKD 507
            ..     .:|.|.|...|.:.::::.:..|..:   :..|.:...|.|....::.:||   |.|.
Human   337 TSAVEQTFFLNTGESGNFTSWRYKVSVTLSGKE---KVNGYIRIALYGSNENSKQYEIFKGSLKP 398

  Fly   508 DA--------EFFAGDI 516
            ||        :|..|.|
Human   399 DASHTCAIDVDFNVGKI 415

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6847	NP_573259.2	Pancreat_lipase_like	185..459	CDD:238363	109/282 (39%)
PNLIPRP2	NP_005387.3	Lipase	18..354	CDD:395099	140/406 (34%)
		Required for galactolipase activity. /evidence=ECO:0000269|PubMed:26494624	93..105		3/11 (27%)
		Required for galactolipase activity. /evidence=ECO:0000269|PubMed:26494624	257..279		6/26 (23%)
		PLAT_PL	357..469	CDD:238857	13/62 (21%)