Protein Alignment CG6847 and PNLIPRP1

DIOPT Version :9

• Sequence 1: NP_001285397.1
• Gene: CG6847 / 32778
• FlyBaseID: FBgn0030884
• Length: 1000
• Species: Drosophila melanogaster
• Sequence 2: NP_001290064.1
• Gene: PNLIPRP1 / 5407
• HGNCID: 9156
• Length: 467
• Species: Homo sapiens
• Alignment Length: 474
• Identity: 153/474 - (32%)
• Similarity: 218/474 - (45%)
• Gaps: 105/474 - (22%)

  Fly    70 KRVCYGELGCFEDSGPFA-----YLEMLPSSPEEINTKFYFYSTRQRSDRPLMELSFLNMTNAFR 129
            |.|||.:||||.|:.|:.     .|::||.|||:|.|:|..|:....::..::.|
Human    18 KEVCYEDLGCFSDTEPWGGTAIRPLKILPWSPEKIGTRFLLYTNENPNNFQILLL---------- 72

  Fly   130 GKRETEVSTSSPEGTSGRSSVASAPSSMSAVNATTFTTERPGGGQKKPTPSIDDLEGFDELSVRV 194
                                     |..|.:.|:.|..:|                     ..|.
Human    73 -------------------------SDPSTIEASNFQMDR---------------------KTRF 91

  Fly   195 IVHGFGSACPHVWIYEMKTALMAVEDCIVICVDWENGATFPNYVRAAANTRLVGKQLAMLLRNLQ 259
            |:|||.......|:.:|...|..||:...|||||:.|:. ..|.:||.|.|:||.|:|.:|..|.
Human    92 IIHGFIDKGDESWVTDMCKKLFEVEEVNCICVDWKKGSQ-ATYTQAANNVRVVGAQVAQMLDILL 155

  Fly   260 QHKGLDLMRTHVIGFSLGAHVSGFAGAELPGLSRITGLDPAGPLFEAQHPKVRLDSSDAEFVDVI 324
            ........:.|:||.||||||:|.||::.|||||||||||....||:...:||||.|||:|||||
Human   156 TEYSYPPSKVHLIGHSLGAHVAGEAGSKTPGLSRITGLDPVEASFESTPEEVRLDPSDADFVDVI 220

  Fly   325 HSNGENLI-LGGLGSWQPMGHVDYYPNGGRVQTGCSNLFVGAVTDF--IWSAQAAEDEEGRSL-- 384
            |::...|| ..|.|:.|.|||:|::||||....||....:..:.|.  ||:..       |..
Human   221 HTDAAPLIPFLGFGTNQQMGHLDFFPNGGESMPGCKKNALSQIVDLDGIWAGT-------RDFVA 278

  Fly   385 CNHRRAYKFFIDSVAPRCLFPAFPCGNYDDFLKGRCFPCAQDDEDLAEGVPRCGNMGYYADRSTG 449
            |||.|:||::::|:.....|.|:||.:|..|...:||||....         |..||:|||:..|
Human   279 CNHLRSYKYYLESILNPDGFAAYPCTSYKSFESDKCFPCPDQG---------CPQMGHYADKFAG 334

  Fly   450 R-----GQLYLLTREEEPFCAHQFQLQIFNSFNDLPLRT-IGRLEAILEGDGGLNETFEI----- 503
            |     .:.:|.|.|...|...::.:.|     .|..|| .|:::..|.|:.|....:.|
Human   335 RTSEEQQKFFLNTGEASNFARWRYGVSI-----TLSGRTATGQIKVALFGNKGNTHQYSIFRGIL 394

  Fly   504 ------SEKDDAEFFAGDI 516
                  |.:.||:...|.|
Human   395 KPGSTHSYEFDAKLDVGTI 413

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6847	NP_001285397.1	Lipase	70..463	CDD:278576	138/407 (34%)
		Pancreat_lipase_like	185..459	CDD:238363	111/283 (39%)
PNLIPRP1	NP_001290064.1	Lipase	18..353	CDD:278576	138/407 (34%)
		Pancreat_lipase_like	52..349	CDD:238363	121/369 (33%)
		PLAT_PL	356..467	CDD:238857	14/63 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165145212
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_28N19
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D247005at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm41317
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11610
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R5841
SonicParanoid	1	1.000	-	-		X699
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	8	7.880