DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6847 and Lipg

DIOPT Version :9

Sequence 1:	NP_001285397.1	Gene:	CG6847 / 32778	FlyBaseID:	FBgn0030884	Length:	1000	Species:	Drosophila melanogaster
Sequence 2:	NP_001012759.1	Gene:	Lipg / 291437	RGDID:	1310740	Length:	493	Species:	Rattus norvegicus

Alignment Length:	507	Identity:	147/507 - (28%)
Similarity:	223/507 - (43%)	Gaps:	143/507 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly   162 ATTFTTERPGGGQK----KPT---------PSI-------DDLE-----------------GFDE 189
            |.:.||.||.|..:    |||         ||:       .|.|                 ||:
  Rat    19 AGSLTTLRPQGSLRDEHHKPTGVPVTITTKPSVTFNIRTSKDPEHEGCNLSLGDSKLLENCGFN- 82

  Fly   190 LSVRV--IVHGFG-SACPHVWIYEMKTALMAVE-DCIVICVDWENGATFP----NYVRAAANTRL 246
            ::.:.  |:||:. |.....|::::.:||...| :..|:.|||     .|    .|:.|.:|||:
  Rat    83 MTAKTFFIIHGWTMSGMFESWLHKLVSALQTREKEANVVVVDW-----LPLAHQLYIDAVSNTRV 142

  Fly   247 VGKQLAMLLRNLQQHKGLDLMRTHVIGFSLGAHVSGFAGAELPG-LSRITGLDPAGPLFEAQHPK 310
            ||:::|.:|..||:.....|...|:||:||||||:|:||..:.| :.||||||||||:||.....
  Rat   143 VGRRVAGMLNWLQEKGEFSLGDVHLIGYSLGAHVAGYAGNFVKGTVGRITGLDPAGPMFEGVDIN 207

  Fly   311 VRLDSSDAEFVDVIHSNGENLILG-GLGSWQPMGHVDYYPNGGRVQTGC------SNLFVGAVTD 368
            .||...||:||||:|:  ..|..| .:|...|:||:|.|||||..|.||      .:...|.:::
  Rat   208 RRLSPDDADFVDVLHT--YTLSFGLSIGIRMPVGHIDIYPNGGDFQPGCGFNDVMGSFAYGTISE 270

  Fly   369 FIWSAQAAEDEEGRSLCNHRRAYKFFIDSVA--PRCLFPAFPCGNYDDFLKGRCFPCAQDDEDLA 431
            .:             .|.|.||...|:||:.  .:..| ||.|.:.:.|.:|.|..|.::
  Rat   271 MV-------------KCEHERAVHLFVDSLVNQDKPSF-AFQCTDPNRFKRGICLSCRKN----- 316

  Fly   432 EGVPRCGNMGYYAD--RSTGRGQLYLLTREEEPFCAHQFQLQI--FNSFN------DLPLRTIGR 486
                ||.|:||.|.  |.....::||.||...||..:.:||::  |:..|      ||.:...|
  Rat   317 ----RCNNIGYNAKKMRKKRNSKMYLKTRAGMPFRVYHYQLKVHMFSYKNSGDIQPDLYITLYG- 376

  Fly   487 LEAILEGDGGLNETFEISEKDDAEFFAGDIVSKIIVPHPALGFPTTLSLHYKSYSGWLSKGLPHW 551
                              ...|::....:||.||     .|....|..::.:.|.|
  Rat   377 ------------------SNADSQNLPLEIVEKI-----ELNATNTFLVYTEEYLG--------- 409

  Fly   552 DIDKVVLT------------DSFGRSHSLCRPSTKLSSGSPVRLRLQAGNCE 591
            |:.|:.||            :.| ||: |.:||:........|:|:::|..:
  Rat   410 DLFKIRLTWEGVSSSWYNLWNEF-RSY-LSQPSSPSRELHIRRIRVKSGETQ 459

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6847	NP_001285397.1	Lipase	70..463	CDD:278576	116/357 (32%)
CG6847	NP_001285397.1	Pancreat_lipase_like	185..459	CDD:238363	103/310 (33%)
Lipg	NP_001012759.1	Pancreat_lipase_like	51..342	CDD:238363	104/321 (32%)
		lipo_lipase	53..488	CDD:132274	136/473 (29%)
		Heparin-binding. /evidence=ECO:0000250	327..339		2/11 (18%)
		PLAT_LPL	349..485	CDD:238856	29/146 (20%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D247005at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11610
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	4.020