DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6847 and Pnliprp2

DIOPT Version :9

Sequence 1:	NP_001285397.1	Gene:	CG6847 / 32778	FlyBaseID:	FBgn0030884	Length:	1000	Species:	Drosophila melanogaster
Sequence 2:	NP_476554.1	Gene:	Pnliprp2 / 117554	RGDID:	620793	Length:	482	Species:	Rattus norvegicus

Alignment Length:	492	Identity:	152/492 - (30%)
Similarity:	230/492 - (46%)	Gaps:	107/492 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    70 KRVCYGELGCFEDSGPFA-----YLEMLPSSPEEINTKFYFYSTRQRSDRPLMELSFLNMTNAFR 129
            |.||||.||||.:..|:|     .|::.|.|||:|:|:|..|:    ::.|          |.::
  Rat    31 KEVCYGHLGCFSNDKPWAGMLQRPLKIFPWSPEDIDTRFLLYT----NENP----------NNYQ 81

  Fly   130 GKRETEVSTSSPEGTSGRSSVASAPSSMSAVNATTFTTERPGGGQKKPTPSIDDLEGFDELSVRV 194
                 ::|.:.|:                .:..:.|..:|                     ..|.
  Rat    82 -----KISATEPD----------------TIKFSNFQLDR---------------------KTRF 104

  Fly   195 IVHGFGSACPHVWIYEMKTALMAVEDCIVICVDWENGATFPNYVRAAANTRLVGKQLAMLLRNLQ 259
            |||||.......|:.:|...:..||....|||||..|:. ..|.:|:.|||:||.::|.|::.|.
  Rat   105 IVHGFIDKGEDGWLLDMCKKMFQVEKVNCICVDWRRGSR-TEYTQASYNTRVVGAEIAFLVQVLS 168

  Fly   260 QHKGLDLMRTHVIGFSLGAHVSGFAGAELPG-LSRITGLDPAGPLFEAQHPKVRLDSSDAEFVDV 323
            ...|......|:||.||||||.|.||..|.| :.||||||||.|.|:....:||||.|||.||||
  Rat   169 TEMGYSPENVHLIGHSLGAHVVGEAGRRLEGHVGRITGLDPAEPCFQGLPEEVRLDPSDAMFVDV 233

  Fly   324 IHSNGENLI-LGGLGSWQPMGHVDYYPNGGRVQTGCSNLFVGAVTDF--IWSAQAAEDEEGRSLC 385
            ||::...:| ..|.|..|.:||:|::||||:...||....:..:.|.  ||     |..:....|
  Rat   234 IHTDSAPIIPYLGFGMSQKVGHLDFFPNGGKEMPGCQKNILSTIVDINGIW-----EGTQNFVAC 293

  Fly   386 NHRRAYKFFIDSVAPRCLFPAFPCGNYDDFLKGRCFPCAQDDEDLAEGVPRCGNMGYYADRSTGR 450
            ||.|:||::..|:.....|..:||.:|:.|.:..||||.:      ||.|:   ||:|||:..|:
  Rat   294 NHLRSYKYYASSILNPDGFLGYPCSSYEKFQQNDCFPCPE------EGCPK---MGHYADQFEGK 349

  Fly   451 -----GQLYLLTREEEPFCAHQFQLQIFNSFNDLPLRTIGRLEAILEGDGGLNETFEISE----- 505
                 ..:||.|.:...|...::::.:..|.   ..:..|.:...|.|:.|.::.:||.:
  Rat   350 TATVEQTVYLNTGDSGNFTRWRYKVSVTLSG---AKKLSGYILVALYGNNGNSKQYEIFKGSLKP 411

  Fly   506 -----KD-DAEFFAGDIV-------SKII-VPHPALG 528
                 :| |.:...|:|.       :|:| :..|.||
  Rat   412 EARHVRDIDVDINVGEIQKVKFLWNNKVINLFRPTLG 448

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6847	NP_001285397.1	Lipase	70..463	CDD:278576	135/406 (33%)
CG6847	NP_001285397.1	Pancreat_lipase_like	185..459	CDD:238363	109/282 (39%)
Pnliprp2	NP_476554.1	Lipase	31..367	CDD:278576	135/406 (33%)
		Pancreat_lipase_like	65..363	CDD:238363	119/368 (32%)
		PLAT_PL	370..482	CDD:238857	16/82 (20%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_28N19
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D247005at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	LDO	PTHR11610
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X699
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.920