Protein Alignment Vps4 and vps4b

DIOPT Version :10

• Sequence 1: NP_573258.1
• Gene: Vps4 / 32777
• FlyBaseID: FBgn0283469
• Length: 442
• Species: Drosophila melanogaster
• Sequence 2: NP_001011154.1
• Gene: vps4b / 496572
• XenbaseID: XB-GENE-1001856
• Length: 443
• Species: Xenopus tropicalis
• Alignment Length: 446
• Identity: 335/446 - (75%)
• Similarity: 383/446 - (85%)
• Gaps: 7/446 - (1%)

  Fly     1 MAA-GTTLQKAIDLVTKATEEDRNKNYAEALRLYEHGVEYFLHTIKYEAQGEKAKDSIRAKCLQY 64
            ||| ||.|||||||.:||::||:..||.||||||:|.|:||||.:||:|||||||.||||||::|
 Frog     1 MAANGTNLQKAIDLASKASQEDKAGNYEEALRLYQHSVQYFLHVVKYDAQGEKAKASIRAKCIEY 65

  Fly    65 LDRAEKLKEYLKKGKK---KPIKEGGESSAKDDKDKKSDSDDEDGDDPEKKKLQSKLEDAIVIEK 126
            |||||:||.||||.:|   ||:|||...||   .||.::||:.|.:|||||||||:|:.|||:||
 Frog    66 LDRAEQLKAYLKKKEKAPAKPVKEGAPRSA---DDKGNESDEGDSEDPEKKKLQSQLQGAIVMEK 127

  Fly   127 PKVQWSDVAGLDAAKEALKEAVILPIKFPQLFTGKRIPWKGILLFGPPGTGKSYLAKAVATEANR 191
            |.|:|:|||||:.||||||||||||||||.||||||.||:||||||||||||||||||||||||.
 Frog   128 PNVKWNDVAGLEGAKEALKEAVILPIKFPHLFTGKRTPWRGILLFGPPGTGKSYLAKAVATEANN 192

  Fly   192 STFFSVSSSDLMSKWLGESEKLVKNLFELARQHKPSIIFIDEIDSMCSARSDNENDSVRRIKTEF 256
            |||||:|||||:|||||||||||||||:|||:|||||||||||||:|.:||:||:::.|||||||
 Frog   193 STFFSISSSDLVSKWLGESEKLVKNLFQLAREHKPSIIFIDEIDSLCGSRSENESEAARRIKTEF 257

  Fly   257 LVQMQGVGNDTDGILVLGATNIPWVLDSAIRRRFEKRIYIPLPEAHARLVMFKIHLGNTTHVLTE 321
            ||||||||.|.:||||||||||||||||||||||||||||||||.|||..|||:|||.|.|.|:|
 Frog   258 LVQMQGVGVDNEGILVLGATNIPWVLDSAIRRRFEKRIYIPLPEEHARADMFKLHLGTTPHSLSE 322

  Fly   322 QDLKELAGKTEGYSGADISIVVRDALMEPVRKVQTATHFKRVSGPSPTNHEEIVNDLLVPCSPGD 386
            .|.:||..||.|||||||||:||||||:||||||:|||||:|.|.||.:.....:|||.||||||
 Frog   323 ADYRELGKKTNGYSGADISIIVRDALMQPVRKVQSATHFKKVQGKSPLDPNVTRDDLLTPCSPGD 387

  Fly   387 QGAVEMNWMDVPSDKLFEPPVTMRDMLKSLSRTKPTVNEDDLKKLRKFTEDFGQEG 442
            ..|:||.|||||.||||||.|.|.||||||:.|||||||:||.||:||||||||||
 Frog   388 PNAIEMTWMDVPGDKLFEPVVCMSDMLKSLAHTKPTVNEEDLAKLKKFTEDFGQEG 443

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Vps4	NP_573258.1	MIT_VPS4	6..69	CDD:239141	44/62 (71%)
		RecA-like_VPS4	126..296	CDD:410929	145/169 (86%)
		AAA_lid_3	323..361	CDD:465537	29/37 (78%)
		Vps4_C	379..439	CDD:462762	45/59 (76%)
vps4b	NP_001011154.1	MIT_VPS4	7..76	CDD:239141	48/68 (71%)
		RecA-like_VPS4	127..297	CDD:410929	145/169 (86%)
		AAA_lid_3	324..365	CDD:465537	31/40 (78%)
		Vps4_C	380..440	CDD:462762	45/59 (76%)