DRSC/TRiP Functional Genomics Resources

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Protein Alignment Vps4 and Katnal2

DIOPT Version :9

Sequence 1:NP_001285396.1 Gene:Vps4 / 32777 FlyBaseID:FBgn0283469 Length:442 Species:Drosophila melanogaster
Sequence 2:XP_006255033.1 Gene:Katnal2 / 307253 RGDID:1564708 Length:537 Species:Rattus norvegicus


Alignment Length:512 Identity:169/512 - (33%)
Similarity:245/512 - (47%) Gaps:125/512 - (24%)


- Green bases have known domain annotations that are detailed below.


  Fly     1 MAAGTTLQKAIDLVTKATEEDRNKNYAEALRLYEHGVEYFLHTIKYEAQGEKAKDSI-------- 57
            |.|...|::...|..:..|...|.:....|..||.  .||:...||....:||.|.:        
  Rat    43 MDAANALEEETKLGLRRFEVCDNVDLETILMEYES--YYFVKFQKYPKVVKKASDQVENNISSRS 105

  Fly    58 --RAKCLQYLDRAEKL-KEYLKKGKKK--PIKEGGESSAKDDKDKKS------------------ 99
              :.|.|.. |..:.| |.|.:|.:.|  .:|.|...|.|:...::|                  
  Rat   106 GGKNKRLTN-DNCQNLPKIYHQKSRPKTSTVKTGDTKSVKEHPKQESVTNAQAESSDFGLNISKI 169

  Fly   100 --DSDDED-------------------------------------------------GDDPEKKK 113
              ||.:|.                                                 |.:.|.::
  Rat   170 HKDSPEEKAHPRRGQIIDFRGLLTDAIKGATSEYALNTFECNPDPSERLLKPLSAFIGMNSEMRE 234

  Fly   114 LQSKLEDAIVIEKPKVQWSDVAGLDAAKEALKEAVILPIKFPQLFTGKRIPWKGILLFGPPGTGK 178
            |.:.:...|.:..|.::|:|:.||||||:.:||||:.||::||||||...||||:||:|||||||
  Rat   235 LAAVVSRDIYLHNPNIKWNDIIGLDAAKQLVKEAVVYPIRYPQLFTGILSPWKGLLLYGPPGTGK 299

  Fly   179 SYLAKAVATEANRSTFFSVSSSDLMSKWLGESEKLVKNLFELARQHKPSIIFIDEIDSMCSARS- 242
            :.||||||||. ::|||::|:|.::|||.|:|||||:.||||||.|.||.||:||::|:.|.|. 
  Rat   300 TLLAKAVATEC-KTTFFNISASTIVSKWRGDSEKLVRVLFELARYHAPSTIFLDELESVMSQRGM 363

  Fly   243 --DNENDSVRRIKTEFLVQMQGVGNDTDGILVLGATNIPWVLDSAIRRRFEKRIYIPLPEAHARL 305
              ..|::...|:|||.||||.|:....|.:.||.|:|:||.||.|:.||.||||.:.||...||.
  Rat   364 VPGGEHEGSLRMKTELLVQMDGLARSEDLVFVLAASNLPWELDCAMLRRLEKRILVDLPSQEARQ 428

  Fly   306 VMF-----KIHLGNTTHVLTEQDLKELAGKTEGYSGADISIVVRDALMEPVRKVQTATHFKRVSG 365
            .|.     .:...:...:.|:.:...|:.:||||||:||.:|.|:|.|.||||:.....      
  Rat   429 AMIYHWLPPVSKNHALELRTQLEYSVLSQETEGYSGSDIKLVCREAAMRPVRKIFNVLE------ 487

  Fly   366 PSPTNHEEIVNDLLVPCSPGDQGAVEMNWMDVPSDKLFEPPVTMRDMLKSLSRTKPT 422
                ||:...::||         .::::            .||..|.|..|:.|||:
  Rat   488 ----NHQSESSNLL---------GIQLD------------TVTTEDFLDVLAHTKPS 519

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Vps4NP_001285396.1 MIT_VPS4 6..69 CDD:239141 17/72 (24%)
RecA-like_VPS4 126..296 CDD:410929 98/172 (57%)
AAA_lid_3 323..361 CDD:407720 17/37 (46%)
Vps4_C 379..439 CDD:401324 9/44 (20%)
Katnal2XP_006255033.1 LisH 25..55 CDD:128913 3/11 (27%)
AAA 285..422 CDD:214640 77/137 (56%)
AAA 289..421 CDD:278434 73/132 (55%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D787710at2759
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 1 1.000 - -
TreeFam 00.000 Not matched by this tool.
32.920

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