DRSC/TRiP Functional Genomics Resources

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Protein Alignment Vps4 and knk1

DIOPT Version :10

Sequence 1:NP_573258.1 Gene:Vps4 / 32777 FlyBaseID:FBgn0283469 Length:442 Species:Drosophila melanogaster
Sequence 2:NP_595275.1 Gene:knk1 / 2541249 PomBaseID:SPBC947.01 Length:660 Species:Schizosaccharomyces pombe


Alignment Length:330 Identity:146/330 - (44%)
Similarity:200/330 - (60%) Gaps:49/330 - (14%)


- Green bases have known domain annotations that are detailed below.


  Fly   122 IVIEKPKVQWSDVAGLDAAKEALKEAVILPIKFPQLFTGKRIPWKGILLFGPPGTGKSYLAKAVA 186
            |:.....|.|||:||||.||.:||||||.|...|:||.|.|.|.:|:||||||||||:.||:|||
pombe   369 IISNHEPVYWSDIAGLDDAKNSLKEAVIYPFLRPELFQGLREPVQGMLLFGPPGTGKTMLARAVA 433

  Fly   187 TEANRSTFFSVSSSDLMSKWLGESEKLVKNLFELARQHKPSIIFIDEIDSMCSARSD--NENDSV 249
            ||| ::||||:|:|.|.||:||:|||||:.|||:|::...|:||:|||||:.|||:|  ||::|.
pombe   434 TEA-KATFFSISASSLTSKYLGDSEKLVRALFEVAKRQTCSVIFVDEIDSILSARNDSGNEHESS 497

  Fly   250 RRIKTEFLVQMQGVGN--------DTDGILVLGATNIPWVLDSAIRRRFEKRIYIPLPEAHARLV 306
            ||:|||||:|...:.|        .:..:|||.|||:||.:|.|.||||.||.||||||...|..
pombe   498 RRLKTEFLIQWSSLTNAAPDKQTGHSPRVLVLAATNLPWCIDEAARRRFVKRTYIPLPEKETRYK 562

  Fly   307 MFKIHLGNTTHVLTEQDLKELAGKTEGYSGADISIVVRDALMEPVRKVQTATHFKRVSGPSPTNH 371
            .....|.|..|.|||:||:||...||||||:||:.:.:||.|.|:|.                  
pombe   563 HLSHLLHNQVHCLTEEDLEELVNLTEGYSGSDITALAKDAAMGPLRN------------------ 609

  Fly   372 EEIVNDLLVPCSPGDQGAVEMNWMDVPSDKLFEPPVTMRDMLKSLSRTKPTVNEDDLKKLRKFTE 436
               :.|.|:..|      .||           .||:::.....||...:|:|:::.:.:..::.:
pombe   610 ---LGDALLTTS------AEM-----------IPPISLNHFKASLRTIRPSVSQEGIHRYEEWNK 654

  Fly   437 DFGQE 441
            .||.:
pombe   655 QFGSQ 659

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Vps4NP_573258.1 MIT_VPS4 6..69 CDD:239141
RecA-like_VPS4 126..296 CDD:410929 102/179 (57%)
AAA_lid_3 323..361 CDD:465537 17/37 (46%)
Vps4_C 379..439 CDD:462762 10/59 (17%)
knk1NP_595275.1 Herpes_BLLF1 <221..>359 CDD:282904
RecA-like_VPS4-like 381..552 CDD:410917 98/171 (57%)
AAA_lid_3 577..614 CDD:465537 19/57 (33%)
Vps4_C <623..657 CDD:462762 6/33 (18%)
Blue background indicates that the domain is not in the aligned region.

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