DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Gss1 and gss

DIOPT Version :9

Sequence 1:	NP_788925.2	Gene:	Gss1 / 32775	FlyBaseID:	FBgn0030882	Length:	562	Species:	Drosophila melanogaster
Sequence 2:	NP_001006104.1	Gene:	gss / 450084	ZFINID:	ZDB-GENE-041010-208	Length:	475	Species:	Danio rerio

Alignment Length:	529	Identity:	210/529 - (39%)
Similarity:	296/529 - (55%)	Gaps:	80/529 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    30 AKDYAIMHGAAMRSK-TAFSPDSLNFAPFVLVPSSFPRKEFEKAVALQPIINRLMHNVAHDEEFI 93
            |||.|::||..||:| |..||:.:::|||.|.|:|.|...|.:|:|:|...|||:..|:.:..|:
Zfish    22 AKDTALLHGVLMRTKDTPNSPEVVSYAPFTLFPTSVPAALFHQALAVQTQFNRLVDRVSQNHSFL 86

  Fly    94 TTTLAETIKVDEFTANLFNIYRKVLAHGFTQKTSLGMLRSDLMLESGCPELSPRALRTAAGEDRG 158
            ..|||.|||||:|||.|||||::|...|..||..:|:.|||.||:
Zfish    87 EDTLASTIKVDDFTARLFNIYKQVQQEGHAQKIVVGLNRSDYMLD-------------------- 131

  Fly   159 QDAGAAVGQIAGANGAAGVGTAAGTGSKEEEHREVQLSRVTKEPERRATGAQSAYCCWKQVEINT 223
                                                     ..|:.|.:        .||:||||
Zfish   132 -----------------------------------------HSPDGRTS--------LKQIEINT 147

  Fly   224 IASGFGHLGPASKTIQRFVLSELGHADKLHNMPDNNALAGLCDGMVKAWDIYAKPQAVILFIIED 288
            ||:.||.|...:..:.|.:|......|:...:.|||..|||..|:.|||::|...:||:||::|:
Zfish   148 IAASFGGLASRTPDVHRHILKVANLPDECSLVLDNNPAAGLAKGLAKAWELYGSKRAVVLFLVEN 212

  Fly   289 VSYNICDQRF--HEFYIRETYPHIKVLRRTLTEVHREGKLGQSKELLLGSQEVAVIYFRAGYEPG 351
            |..||.|.|:  :|.:.|    :|.|:||...:|.|.|.|.:||.|.:...|||::|||.||.|.
Zfish   213 VQRNIYDHRYVENELWKR----NIPVIRRQFEDVFRTGSLDESKRLFVDGHEVAIVYFRNGYMPQ 273

  Fly   352 HYHSQADWDARYLMETSLAIKCPSIHYHLAGTKKVQQALAQPAVLERFIND-PEEIKAVGKIFTG 415
            :|.|:..|:.|.:||.|:|:|||.|..||||||:|||.||:|.|||.|..| ||.:..:...|.|
Zfish   274 NYTSEQSWEVRLMMERSVAVKCPDISTHLAGTKEVQQELARPGVLECFFPDEPETVSQIRATFAG 338

  Fly   416 LYSLDDNEAGNASYEMALRTPERFVLKPQREGGGNNVYGVDIPDALKRM-SRVERSAWILMDLIH 479
            ||:||..|.|:.:..|||..|:::||||||||||||:||.:|.:.|::: :..||:|:||||.|.
Zfish   339 LYTLDMGEEGDNTVAMALANPDQYVLKPQREGGGNNIYGSEICEVLEKLKNSSERTAYILMDKIQ 403

  Fly   480 PPLTKGYMVRPGGDMPPQIVDMVSELGIFGVVIGDAEHIVHNYQAGHMLRTKLSTANEGGVAAGL 544
            |...:..::|||.  |.::...:||||.||..:.....:|.|...||:||||.|...:||||||:
Zfish   404 PVPVQNILLRPGA--PLKVSSCLSELGAFGAYVRKGSELVLNECVGHLLRTKSSEHADGGVAAGV 466

  Fly   545 GALDSPYLI 553
            ..||:|.|:
Zfish   467 AVLDNPLLV 475

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Gss1	NP_788925.2	GSH_synth_ATP	20..552	CDD:281854	209/526 (40%)
gss	NP_001006104.1	GSH_synth_ATP	12..474	CDD:281854	209/526 (40%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170580928
Domainoid	1	1.000	291	1.000	Domainoid score	I1503
eggNOG	1	0.900	-	-		E1_KOG0021
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H148
Inparanoid	1	1.050	396	1.000	Inparanoid score	I1907
OMA	1	1.010	-	-		QHG54115
OrthoDB	1	1.010	-	-		D1189955at2759
OrthoFinder	1	1.000	-	-		FOG0005180
OrthoInspector	1	1.000	-	-		oto39559
orthoMCL	1	0.900	-	-		OOG6_101596
Panther	1	1.100	-	-	LDO	PTHR11130
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R528
SonicParanoid	1	1.000	-	-		X3696
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	16	15.800