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Protein Alignment Gss1 and GSS

DIOPT Version :9

Sequence 1:	NP_788925.2	Gene:	Gss1 / 32775	FlyBaseID:	FBgn0030882	Length:	562	Species:	Drosophila melanogaster
Sequence 2:	NP_000169.1	Gene:	GSS / 2937	HGNCID:	4624	Length:	474	Species:	Homo sapiens

Alignment Length:	537	Identity:	200/537 - (37%)
Similarity:	283/537 - (52%)	Gaps:	81/537 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    20 EDELLEVTAKAKDYAIMHGAAMR-SKTAFSPDSLNFAPFVLVPSSFPRKEFEKAVALQPIINRLM 83
            :.:|.|:..:|.|.|:..|..:| |:...|.:.:::|||.|.||..|....|:|.|:|...|.|:
Human    12 KQQLEELARQAVDRALAEGVLLRTSQEPTSSEVVSYAPFTLFPSLVPSALLEQAYAVQMDFNLLV 76

  Fly    84 HNVAHDEEFITTTLAETIKVDEFTANLFNIYRKVLAHGFTQKTSLGMLRSDLMLESGCPELSPRA 148
            ..|:.:..|:..||:.|||.|:|||.||:|:::||..|..|...||:.|||.|.:
Human    77 DAVSQNAAFLEQTLSSTIKQDDFTARLFDIHKQVLKEGIAQTVFLGLNRSDYMFQ---------- 131

  Fly   149 LRTAAGEDRGQDAGAAVGQIAGANGAAGVGTAAGTGSKEEEHREVQLSRVTKEPERRATGAQSAY 213
                    |..|...|:
Human   132 --------RSADGSPAL------------------------------------------------ 140

  Fly   214 CCWKQVEINTIASGFGHLGPASKTIQRFVLSELGHADKLHNMPDNNALAGLCDGMVKAWDIYAKP 278
               ||:|||||::.||.|...:..:.|.|||.|....:...:..||...||..|:.|||::|..|
Human   141 ---KQIEINTISASFGGLASRTPAVHRHVLSVLSKTKEAGKILSNNPSKGLALGIAKAWELYGSP 202

  Fly   279 QAVILFIIEDVSYNICDQRF--HEFYIRETYPHIKVLRRTLTEVHREGKLGQSKELLLGSQEVAV 341
            .|::|.|.::...||.|||.  :|...|    :|.|:|||..::..:|.|.|.:.|.:..||:||
Human   203 NALVLLIAQEKERNIFDQRAIENELLAR----NIHVIRRTFEDISEKGSLDQDRRLFVDGQEIAV 263

  Fly   342 IYFRAGYEPGHYHSQADWDARYLMETSLAIKCPSIHYHLAGTKKVQQALAQPAVLERFI-NDPEE 405
            :|||.||.|..|..| :|:||.|:|.|.|.|||.|...|||||||||.|::|.:||..: ..||.
Human   264 VYFRDGYMPRQYSLQ-NWEARLLLERSHAAKCPDIATQLAGTKKVQQELSRPGMLEMLLPGQPEA 327

  Fly   406 IKAVGKIFTGLYSLDDNEAGNASYEMALRTPERFVLKPQREGGGNNVYGVDIPDALKRM-SRVER 469
            :..:...|.||||||..|.|:.:...||..|.||||||||||||||:||.::..|||:: ...||
Human   328 VARLRATFAGLYSLDVGEEGDQAIAEALAAPSRFVLKPQREGGGNNLYGEEMVQALKQLKDSEER 392

  Fly   470 SAWILMDLIHPPLTKGYMVRPGGDMPPQIVDMVSELGIFGVVIGDAEHIVHNYQAGHMLRTKLST 534
            :::|||:.|.|...:..::|||.  |.::|..:||||||||.:...:.:|.|...||:||||...
Human   393 ASYILMEKIEPEPFENCLLRPGS--PARVVQCISELGIFGVYVRQEKTLVMNKHVGHLLRTKAIE 455

  Fly   535 ANEGGVAAGLGALDSPY 551
            ..:||||||:..||:||
Human   456 HADGGVAAGVAVLDNPY 472

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.