DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6788 and FIBCD1

DIOPT Version :9

Sequence 1:	NP_573254.1	Gene:	CG6788 / 32773	FlyBaseID:	FBgn0030880	Length:	358	Species:	Drosophila melanogaster
Sequence 2:	NP_001138578.1	Gene:	FIBCD1 / 84929	HGNCID:	25922	Length:	461	Species:	Homo sapiens

Alignment Length:	367	Identity:	109/367 - (29%)
Similarity:	169/367 - (46%)	Gaps:	71/367 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    49 ILDRFAKVNSS--------------------------DELKNQVNAMSETIKDLQT-----RIGH 82
            :.|.||::.|:                          |.|.:|:..:.....:|||     |.||
Human   101 LTDSFARLESAQASVLQALTEHQAQPRLVGDQEQELLDTLADQLPRLLARASELQTECMGLRKGH 165

  Fly    83 KNELLLLQAGQ----IKDQSARLNVLIKNMKVLRSECLNAQAEI-----KSKDI-----QIQLSA 133
            ..      .||    ::.:..||..|:...:...:..:|:.::|     :.:.:     :..|..
Human   166 GT------LGQGLSALQSEQGRLIQLLSESQGHMAHLVNSVSDILDALQRDRGLGRPRNKADLQR 224

  Fly   134 AKIKQMSNELVTQCSRQDTC---PIDGK--GGIYKLKIRELPA-FEAPC----SSNGWLTIQKRY 188
            |..:..........||...|   .:.|:  .|:|.:.....|| |:..|    ...||...|:|.
Human   225 APARGTRPRGCATGSRPRDCLDVLLSGQQDDGVYSVFPTHYPAGFQVYCDMRTDGGGWTVFQRRE 289

  Fly   189 DGAENFDRGWKDYKDGFGRVRGEFFIGLEKVHLMTRQRRHELYIKLGKIDGTTSHAHYDNFELG- 252
            ||:.||.|||..|:|||||:.||.::||:::|.:|.|..:||::.|...:..|::|.|.:|.:|
Human   290 DGSVNFFRGWDAYRDGFGRLTGEHWLGLKRIHALTTQAAYELHVDLEDFENGTAYARYGSFGVGL 354

  Fly   253 ----GEIESYELKSLGRYNGTAGDSLRPHERQKFTTNDKDNDAYRFNCAADEYGGWWYYDCAKSM 313
                .|.:.|.| ::..|:|||||||..|...:|||.|:|:|....||||...|.|||.:|..|.
Human   355 FSVDPEEDGYPL-TVADYSGTAGDSLLKHSGMRFTTKDRDSDHSENNCAAFYRGAWWYRNCHTSN 418

  Fly   314 LNGKFYKEGRSRNGKTNGILWGSWHNNDWTYSLTFVEMMIRP 355
            |||::.:...:  ...:|:.|.||  ..|.|||.|.||.|||
Human   419 LNGQYLRGAHA--SYADGVEWSSW--TGWQYSLKFSEMKIRP 456

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6788	NP_573254.1	FReD	160..356	CDD:238040	83/206 (40%)
FIBCD1	NP_001138578.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..24
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	214..238		2/23 (9%)
		FReD	241..457	CDD:238040	85/221 (38%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2579
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H122246
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000029
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR19143
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X25
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	6	5.910