DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6788 and Fcna

DIOPT Version :9

Sequence 1:	NP_573254.1	Gene:	CG6788 / 32773	FlyBaseID:	FBgn0030880	Length:	358	Species:	Drosophila melanogaster
Sequence 2:	NP_112638.2	Gene:	Fcna / 83517	RGDID:	621221	Length:	335	Species:	Rattus norvegicus

Alignment Length:	204	Identity:	81/204 - (39%)
Similarity:	111/204 - (54%)	Gaps:	26/204 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly   153 CPIDGKGGIYKLKIRELPAFEAPCSSNGWLTIQKRYDGAENFDRGWKDYKDGFGRVRGEFFIGLE 217
            |.:|..||                   ||...|:|.||:.||.|.|..||.|||.:..||::|.:
  Rat   154 CDMDVDGG-------------------GWTVFQRRVDGSINFYRDWDSYKRGFGNLGTEFWLGND 199

  Fly   218 KVHLMTRQRRHELYIKLGKIDGTTSHAHYDNFELGGEIESYELKSLGRY-NGTAGDSLRPHERQK 281
            .:||:|.....||.:.|.:..|.||.|.|.:|::.||.|.|:| :||:: .|||||||..|....
  Rat   200 YLHLLTANGNQELRVDLREFQGQTSFAKYSSFQVSGEQEKYKL-TLGQFLEGTAGDSLTKHNNMA 263

  Fly   282 FTTNDKDNDAY-RFNCAADEYGGWWYYDCAKSMLNGKFYKEGRSRNGKTNGILWGSWHNNDWTYS 345
            |:|:|:|||.. ..||||..:|.|||:||.:|.|||: |..| |.....:||.|.|...:.::|.
  Rat   264 FSTHDQDNDTNGGKNCAALFHGAWWYHDCHQSNLNGR-YLPG-SHESYADGINWLSGRGHRYSYK 326

  Fly   346 LTFVEMMIR 354
            :  .||.||
  Rat   327 V--AEMKIR 333

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6788	NP_573254.1	FReD	160..356	CDD:238040	78/197 (40%)
Fcna	NP_112638.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	47..114
		Collagen	<67..108	CDD:396114
		FReD	123..333	CDD:238040	79/202 (39%)
		A domain, contributes to trimerization. /evidence=ECO:0000250	123..162		4/26 (15%)
		B domain, contributes to trimerization. /evidence=ECO:0000250	163..251		36/88 (41%)
		Carbohydrate-binding. /evidence=ECO:0000250\|UniProtKB:O00602	291..293		1/1 (100%)
		P domain. /evidence=ECO:0000250\|UniProtKB:O00602	326..335		4/10 (40%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2579
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000029
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X25
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	5.810