DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG6788 and tnr

DIOPT Version :9

Sequence 1:	NP_573254.1	Gene:	CG6788 / 32773	FlyBaseID:	FBgn0030880	Length:	358	Species:	Drosophila melanogaster
Sequence 2:	NP_919364.1	Gene:	tnr / 369191	ZFINID:	ZDB-GENE-030804-1	Length:	1350	Species:	Danio rerio

Alignment Length:	332	Identity:	104/332 - (31%)
Similarity:	163/332 - (49%)	Gaps:	49/332 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    56 VNSSDELKNQVNAMSETIKDLQTRIGHKNELLLLQ-----------AGQIKDQSARLNVLIKNMK 109
            :.|...:.|.|..|........:.|.|::.|:..|           ..:..|.|.:..:|.....
Zfish  1021 LTSGTVISNFVTPMDAPQNLTASEINHRSALISWQPPIADIDNYMLTYKAADGSRKELILDAEDT 1085

  Fly   110 VLRSECLNAQAEIKSKDIQIQLSAAKIKQMSNELVTQCS---------RQDTCP---IDGK--GG 160
            .:|.|.|   ||.....:::|::    :.:...::...|         ....|.   ::|:  ||
Zfish  1086 WIRLEGL---AETTEYTVRLQVA----RGLETSVIVSTSFTTGNRLFPTPQNCAQHLLNGETLGG 1143

  Fly   161 IYKLKI-REL-PAFEAPC----SSNGWLTIQKRYDGAENFDRGWKDYKDGFGRVRGEFFIGLEKV 219
            ||.:.: |:| ...:..|    ...||:..|:|.:|..:|.|.|.|||.|||.:..||::||:.:
Zfish  1144 IYTIYVNRDLSQGVQVYCDMTTDGGGWIVFQRRQNGLTDFSRKWTDYKIGFGSLEDEFWLGLDNI 1208

  Fly   220 HLMTRQRRHELYIKLGKIDGTTS-HAHYDNFELGGEIESYELKSLGRYNGTAGDSLRPHERQKFT 283
            |.:..|.|:||.|.:.  ||..| :|:||.|.:|.....|:|: :|.|:|||||||..|:.:.|:
Zfish  1209 HKIAAQGRYELRIDMK--DGQESVYANYDRFSIGDSKSLYKLR-IGEYSGTAGDSLSYHQSRPFS 1270

  Fly   284 TNDKDNDAYRFNCAADEYGGWWYYDCAKSMLNGKFYKEGRSRNGKTNGILWGSWHNNDWTYSLTF 348
            |.|||||....|||....|.|||.:|.::.||||:   |.||:  :.||.|..|..::  :|:.|
Zfish  1271 TKDKDNDIAVTNCALSYKGAWWYKNCHRANLNGKY---GESRH--SQGINWYHWKGHE--FSIPF 1328

  Fly   349 VEMMIRP 355
            |||.:||
Zfish  1329 VEMKMRP 1335

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6788	NP_573254.1	FReD	160..356	CDD:238040	83/203 (41%)
tnr	NP_919364.1	EGF_2	199..225	CDD:285248
		EB	234..283	CDD:279949
		EGF_2	294..318	CDD:285248
		fn3	323..401	CDD:278470
		fn3	411..490	CDD:278470
		fn3	500..579	CDD:278470
		FN3	590..674	CDD:238020
		fn3	682..754	CDD:278470
		fn3	771..849	CDD:278470
		FN3	859..935	CDD:214495
		fn3	949..1019	CDD:278470
		fn3	1035..1103	CDD:278470	12/70 (17%)
		FReD	1126..1336	CDD:238040	86/220 (39%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2579
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR19143
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	4	3.910