DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6788 and Fga

DIOPT Version :9

Sequence 1:	NP_573254.1	Gene:	CG6788 / 32773	FlyBaseID:	FBgn0030880	Length:	358	Species:	Drosophila melanogaster
Sequence 2:	NP_001008724.1	Gene:	Fga / 361969	RGDID:	2603	Length:	782	Species:	Rattus norvegicus

Alignment Length:	343	Identity:	103/343 - (30%)
Similarity:	152/343 - (44%)	Gaps:	76/343 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    81 GHKNELLLL--QAGQIKDQSARLNVLIKNMKVLRSECLNA--------------QAEIKSKDIQI 129
            |..:||..:  :.|...|  :|...|..|.|...|:..::              :....||...:
  Rat   448 GRLDELSRMHPELGSFYD--SRFGSLTSNFKEFGSKTSDSDIFTDIENPSSHVPEFSSSSKTSTV 510

  Fly   130 QLSAAKIKQMSNELVTQCSRQ---------------------DTCPIDGKGGIYKLKIRELPA-- 171
            :....|..:|::|..::..::                     .|.|...:.||:.:|   ||.
  Rat   511 RKQVTKSYKMADEAASEAHQEGDTRTTKRGRARTMRDCDDVLQTHPSGAQNGIFSIK---LPGSS 572

  Fly   172 --FEAPC----SSNGWLTIQKRYDGAENFDRGWKDYKDGFGRV----RGEFFIGLEKVHLMTRQR 226
              |...|    |..|||.||:|.||:.||:|.|:|||.|||.:    .|||::|.:.:||:| .|
  Rat   573 KIFSVYCDQETSLGGWLLIQQRMDGSLNFNRTWQDYKRGFGSLNDKGEGEFWLGNDYLHLLT-LR 636

  Fly   227 RHELYIKLGKIDGTTSHAHYDNFELGGEIESYELKSLGRYNGTAGDSL-----------RPHERQ 280
            ...|.::|....|..::|.| :|.:|.|.|.|.|: :..|.|||||:|           ..|...
  Rat   637 GSVLRVELEDWAGKEAYAEY-HFRVGSEAEGYALQ-VSSYQGTAGDALMEGSVEEGTEYTSHSNM 699

  Fly   281 KFTTNDKDNDAYRFNCAADEYGGWWYYDCAKSMLNGKFYKEGR--SRNGK----TNGILWGSWHN 339
            :|:|.|:|.|.:..|||....|||||..|..:.|||.:|..|.  .||..    .||::|..:..
  Rat   700 QFSTFDRDADQWEENCAEVYGGGWWYNSCQAANLNGIYYPGGTYDPRNNSPYEIENGVVWVPFRG 764

  Fly   340 NDWTYSLTFVEMMIRPRI 357
            .|  |||..|.|.|||.:
  Rat   765 AD--YSLRAVRMKIRPLV 780

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6788	NP_573254.1	FReD	160..356	CDD:238040	85/224 (38%)
Fga	NP_001008724.1	Fib_alpha	51..189	CDD:285864
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	264..374
		Fibrinogen_aC	388..453	CDD:288972	1/4 (25%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	522..542		1/19 (5%)
		FReD	546..779	CDD:238040	87/240 (36%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2579
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900