DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6788 and tncb

DIOPT Version :9

Sequence 1:	NP_573254.1	Gene:	CG6788 / 32773	FlyBaseID:	FBgn0030880	Length:	358	Species:	Drosophila melanogaster
Sequence 2:	NP_001299845.1	Gene:	tncb / 30037	ZFINID:	ZDB-GENE-980526-104	Length:	1811	Species:	Danio rerio

Alignment Length:	365	Identity:	92/365 - (25%)
Similarity:	144/365 - (39%)	Gaps:	76/365 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    15 SLSISTSLANDPQRSFDQNADNPCSAHRIWVWRP----ILDRFAKVNSSDEL------------- 62
            |.:.||....|.....:..|.|..:...:..|:|    |........|:|.:
Zfish  1486 SAATSTDFTTDVDAPQNLAASNIQTETAMLTWKPPRADISGYILSFESADGVVKEVVLSPTATFY 1550

  Fly    63 -KNQVNAMSETIKDLQTRIGHKNELLLLQAGQIKDQSARLNVLIKNMKVLRSECLNAQAEIKSKD 126
             .:|:.|.:|....||...|.|...:      |......:.||.|:.|......||.
Zfish  1551 SMSQLTASTEYTVKLQAIAGPKRSRV------ISTVFLTIGVLYKHPKDCSQALLNG-------- 1601

  Fly   127 IQIQLSAAKIKQMSNELVTQCSRQDTCPIDGKGGIYKLKIR--ELPAFEAPC----SSNGWLTIQ 185
                                         |...|:|.:.:|  |....:..|    ...||:...
Zfish  1602 -----------------------------DTTSGLYTIYLRGDESQPLQVYCDMTTDGGGWIVFV 1637

  Fly   186 KRYDGAENFDRGWKDYKDGFGRVRGEFFIGLEKVHLMTRQRRHELYIKLGKIDGTTSHAHYDNFE 250
            :|..|...|.|.||:|..|||.:..||::||..:|.:|...::||.:.| :..|.:::|.||.|.
Zfish  1638 RRQSGKVEFFRNWKNYTAGFGDLNDEFWLGLSNLHKITSFGQYELRVDL-RDKGESAYAQYDKFS 1701

  Fly   251 LGGEIESYELKSLGRYNGTAGDSLRPHERQKFTTNDKDNDAYRFNCAADEYGGWWYYDCAKSMLN 315
            :......|:: .:|.|:||||||:..|..:.|:|.|.|||....|||....|.:||.:|.:..:.
Zfish  1702 ISEPRARYKV-HVGGYSGTAGDSMTYHHGRPFSTYDNDNDIAVTNCALSYKGAFWYKNCHRVNIM 1765

  Fly   316 GKFYKEGRSRNGKTNGILWGSWHNNDWTYSLTFVEMMIRP 355
            |::     ..|..:.|:.|..|..::  :|:.|.||.|||
Zfish  1766 GRY-----GDNSHSKGVNWFHWKGHE--HSVEFAEMKIRP 1798

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6788	NP_573254.1	FReD	160..356	CDD:238040	66/202 (33%)
tncb	NP_001299845.1	DnaJ	<471..>544	CDD:333066
		fn3	689..760	CDD:306538
		fn3	778..858	CDD:306538
		fn3	868..948	CDD:306538
		FN3	958..1047	CDD:238020
		fn3	1050..1128	CDD:306538
		fn3	1140..1215	CDD:306538
		fn3	1231..1303	CDD:306538
		fn3	1323..1400	CDD:306538
		fn3	1410..1482	CDD:306538
		fn3	1498..1570	CDD:306538	12/71 (17%)
		FReD	1589..1798	CDD:238040	69/254 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2579
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810