DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6788 and CG30281

DIOPT Version :9

Sequence 1:	NP_573254.1	Gene:	CG6788 / 32773	FlyBaseID:	FBgn0030880	Length:	358	Species:	Drosophila melanogaster
Sequence 2:	NP_726164.1	Gene:	CG30281 / 246525	FlyBaseID:	FBgn0050281	Length:	291	Species:	Drosophila melanogaster

Alignment Length:	287	Identity:	100/287 - (34%)
Similarity:	155/287 - (54%)	Gaps:	36/287 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    86 LLLLQAGQIKD--QSARLNVLIKNMKVLRSECLNAQAEIKSKDIQIQLSAAKIKQMSNELVTQCS 148
            :|:|..|.:..  ||.:|:::.|          .|::.:.|..|:::    ::||...|:..:..
  Fly     8 VLILSGGSLLSTAQSNKLDLVYK----------KAESMVSSLKIRLE----ELKQSYKEITEERG 58

  Fly   149 RQDT-----CPIDG--KGGIYKLKIRELPAFEAPC----SSNGWLTIQKRYDGAENFDRGWKDYK 202
            ..:|     |...|  ..||:.:::..|..|...|    :.:||..||:|.||:|||.|.|::|.
  Fly    59 SHETINPSSCLAAGINSNGIHVIEVPGLEPFPVYCDTRLAGSGWTVIQRRQDGSENFYRCWEEYS 123

  Fly   203 DGFGRVRGEFFIGLEKVHLMTRQRRHELYIKLGKIDGTTSHAHYDNFELGGEIESYELKSLGRYN 267
            .|||.:.||||:||||:|.:|....:||::.:...:|....|.|::|.:|....||.|..||:|:
  Fly   124 QGFGELSGEFFMGLEKLHFLTTAEPYELFVYMEDFNGVVHDARYEDFAIGNASASYALSVLGKYS 188

  Fly   268 GTAGDSLRPHERQKFTTNDKDNDAYRFNCAADEYGGWWYYDCAKSMLNGKFYKEGR---SRNGKT 329
            |.||||||.|:...|:|.|.|:..:  .||....|.|||..|.:|.|||::.:.||   ..:|:
  Fly   189 GDAGDSLRYHKGMPFSTFDHDDTGH--GCARIYVGAWWYDQCQRSNLNGQYLEGGRFEPKMSGR- 250

  Fly   330 NGILWGSWHNNDWTYSLTFVEMMIRPR 356
             ||.|.||...|:.|.  ||:|||||:
  Fly   251 -GITWMSWRGYDYGYK--FVQMMIRPK 274

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6788	NP_573254.1	FReD	160..356	CDD:238040	83/202 (41%)
CG30281	NP_726164.1	FReD	63..274	CDD:238040	85/216 (39%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45446508
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2579
Homologene	1	1.000	-	-		H122246
Inparanoid	1	1.050	91	1.000	Inparanoid score	I3666
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D84222at33392
OrthoFinder	1	1.000	-	-		FOG0000029
OrthoInspector	1	1.000	-	-		otm14151
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR19143
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X25
	10	9.900