DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG6788 and FCN1

DIOPT Version :9

Sequence 1:NP_573254.1 Gene:CG6788 / 32773 FlyBaseID:FBgn0030880 Length:358 Species:Drosophila melanogaster
Sequence 2:NP_001994.2 Gene:FCN1 / 2219 HGNCID:3623 Length:326 Species:Homo sapiens


Alignment Length:204 Identity:74/204 - (36%)
Similarity:100/204 - (49%) Gaps:25/204 - (12%)


- Green bases have known domain annotations that are detailed below.


  Fly   153 CPIDGKGGIYKLKIRELPAFEAPCSSNGWLTIQKRYDGAENFDRGWKDYKDGFGRVRGEFFIGLE 217
            |.:|..||                   ||...|:|.||:.:|.|.|..||.|||...|||::|.:
Human   146 CDMDTDGG-------------------GWTVFQRRMDGSVDFYRDWAAYKQGFGSQLGEFWLGND 191

  Fly   218 KVHLMTRQRRHELYIKLGKIDGTTSHAHYDNFELGGEIESYELKSLGRY-NGTAGDSLRPHERQK 281
            .:|.:|.|...||.:.|...:|....|.|.:|::..|.|.|:| .||.: .|:||:||..|....
Human   192 NIHALTAQGSSELRVDLVDFEGNHQFAKYKSFKVADEAEKYKL-VLGAFVGGSAGNSLTGHNNNF 255

  Fly   282 FTTNDKDNDAYRFNCAADEYGGWWYYDCAKSMLNGKFYKEGRSRNGKTNGILWGSWHNNDWTYSL 346
            |:|.|:|||....|||....|.|||.||..|.||| .|..| ......|||.|.:.....::|.:
Human   256 FSTKDQDNDVSSSNCAEKFQGAWWYADCHASNLNG-LYLMG-PHESYANGINWSAAKGYKYSYKV 318

  Fly   347 TFVEMMIRP 355
            :  ||.:||
Human   319 S--EMKVRP 325

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG6788NP_573254.1 FReD 160..356 CDD:238040 71/197 (36%)
FCN1NP_001994.2 Collagen 51..107 CDD:189968
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 72..111
FReD 115..325 CDD:238040 72/202 (36%)
A domain, contributes to trimerization 115..154 4/26 (15%)
B domain, contributes to trimerization 155..243 33/88 (38%)
Carbohydrate-binding. /evidence=ECO:0000269|PubMed:17897951 282..284 1/1 (100%)
P domain. /evidence=ECO:0000303|PubMed:17148457 317..326 4/11 (36%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG2579
Hieranoid 1 1.000 - -
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 1 1.000 - - FOG0000029
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 1 1.000 - - X25
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
54.810

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