DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6788 and Angptl2

DIOPT Version :9

Sequence 1:	NP_573254.1	Gene:	CG6788 / 32773	FlyBaseID:	FBgn0030880	Length:	358	Species:	Drosophila melanogaster
Sequence 2:	NP_598253.2	Gene:	Angptl2 / 171100	RGDID:	620004	Length:	493	Species:	Rattus norvegicus

Alignment Length:	488	Identity:	127/488 - (26%)
Similarity:	194/488 - (39%)	Gaps:	157/488 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly    14 LSLSISTSLANDPQRSFDQNADNPCSAHRIWVWRPILDRFAKVNSSDE-------LKNQ------ 65
            |.|..:...|..|:...:...|   .:.|.:::   |:|:.:...|.:       :..|
  Rat    11 LGLLATVGAATGPEADVEGAED---GSQREYIY---LNRYKRAGESPDKCTYTFIVPQQRVTGAI 69

  Fly    66 -VNAMSETIKDLQTRIGHKNEL------LLLQAGQIKDQSARLNV---LIKNMKVLRSECLNAQA 120
             ||:....: .|:.|: ||.||      ||.|..||:.....:.|   ::..:|:||.|..|..:
  Rat    70 CVNSKEPEV-HLENRV-HKQELELLNNELLKQKRQIETLQQLVEVDGGIVSEVKLLRKESRNMNS 132

  Fly   121 E------------IKSKDIQIQLS----------------AAKIKQM-------------SNELV 144
            .            |:.:|..::||                |:|.|.:             .:|::
  Rat   133 RVTQLYMQLLHEIIRKRDNALELSQLENRILNQTADMLQLASKYKDLEHKFQHLAMLAHNQSEVI 197

  Fly   145 TQ----CSRQDTC------PIDGKGGIYK---------------------LKI--RELPAFEA-- 174
            .|    |.|....      |......:|:                     ||:  ..||...|
  Rat   198 AQLEEHCQRVPAARPVPQPPPATPPRVYQPPTYNRIINQISTNEIQSDQNLKVLPPSLPTMPALT 262

  Fly   175 --PCSSN---------------------------------------------GWLTIQKRYDGAE 192
              |.|::                                             ||..||:|.||:.
  Rat   263 SLPSSTDKPSGPWRDCLQALEDGHSTSSIYLVKPENTNRLMQVWCDQRHDPGGWTVIQRRLDGSV 327

  Fly   193 NFDRGWKDYKDGFGRVRGEFFIGLEKVHLMTRQRRHELYIKLGKIDGTTSHAHYDNFELGGEIES 257
            ||.|.|:.||.|||.:.||:::|||.::.:|.|..::|.:.:....|....|.|.:|.|..|.|.
  Rat   328 NFFRNWETYKQGFGNIDGEYWLGLENIYWLTNQGNYKLLVTMEDWSGRKVFAEYASFRLEPESEY 392

  Fly   258 YELKSLGRYNGTAGDSLRPHERQKFTTNDKDNDAYRFNCAADEYGGWWYYDCAKSMLNGKFYKEG 322
            |:|: ||||:|.||||...|..::|||.|:|:|.|..|||..:.|||||..||.|.|||.:|:.|
  Rat   393 YKLR-LGRYHGNAGDSFTWHNGKQFTTLDRDHDVYTGNCAHYQKGGWWYNACAHSNLNGVWYRGG 456

  Fly   323 RSRNGKTNGILWGSWHNNDWTYSLTFVEMMIRP 355
            ..|:...:|:.|..:...  :|||..|.|||||
  Rat   457 HYRSRYQDGVYWAEFRGG--SYSLKKVVMMIRP 487

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6788	NP_573254.1	FReD	160..356	CDD:238040	86/268 (32%)
Angptl2	NP_598253.2	t_SNARE	156..>206	CDD:197699	7/49 (14%)
Angptl2	NP_598253.2	FReD	273..487	CDD:238040	76/216 (35%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2579
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm12326
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X25
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.810