DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6788 and Fga

DIOPT Version :9

Sequence 1:	NP_573254.1	Gene:	CG6788 / 32773	FlyBaseID:	FBgn0030880	Length:	358	Species:	Drosophila melanogaster
Sequence 2:	NP_001104518.1	Gene:	Fga / 14161	MGIID:	1316726	Length:	789	Species:	Mus musculus

Alignment Length:	386	Identity:	107/386 - (27%)
Similarity:	159/386 - (41%)	Gaps:	96/386 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly    25 DPQRSFDQNADNPCSAHRIWVWRPILDRFAKVNSSDELKNQVNAMSETIKDLQTRIGHKNELLLL 89
            |...||..:.|.....|      |.|..|        ..|....:|...|:..::....:::|.
Mouse   445 DISHSFSGSLDELSERH------PDLSGF--------FDNHFGLISPNFKEFGSKTHSDSDILT- 494

  Fly    90 QAGQIKDQSARLNVLIKNMKVLRSECLNAQAEIKSKDIQIQLSAAKIKQMSNELVTQCSRQ---- 150
               .|:|.|:.:                .:....||...::....|..:|::|..::..|:
Mouse   495 ---NIEDPSSHV----------------PEFSSSSKTSTVKKQVTKTYKMADEAGSEAHREGETR 540

  Fly   151 -------------------DTCPIDGKGGIYKLKIRELP-----AFEAPC----SSNGWLTIQKR 187
                               .|.....:.||:.:|    |     .|...|    |..|||.||:|
Mouse   541 NTKRGRARARPTRDCDDVLQTQTSGAQNGIFSIK----PPGSSKVFSVYCDQETSLGGWLLIQQR 601

  Fly   188 YDGAENFDRGWKDYKDGFGRV----RGEFFIGLEKVHLMTRQRRHELYIKLGKIDGTTSHAHYDN 248
            .||:.||:|.|:|||.|||.:    .|||::|.:.:||:| .|...|.::|....|..::|.| :
Mouse   602 MDGSLNFNRTWQDYKRGFGSLNDKGEGEFWLGNDYLHLLT-LRGSVLRVELEDWAGKEAYAEY-H 664

  Fly   249 FELGGEIESYELKSLGRYNGTAGDSL-----------RPHERQKFTTNDKDNDAYRFNCAADEYG 302
            |.:|.|.|.|.|: :..|.|||||:|           ..|...:|:|.|:|.|.:..|||....|
Mouse   665 FRVGSEAEGYALQ-VSSYRGTAGDALVQGSVEEGTEYTSHSNMQFSTFDRDADQWEENCAEVYGG 728

  Fly   303 GWWYYDCAKSMLNGKFYKEGR--SRNGK----TNGILWGSWHNNDWTYSLTFVEMMIRPRI 357
            ||||..|..:.|||.:|..|.  .||..    .||::|..:...|  |||..|.|.|||.:
Mouse   729 GWWYNSCQAANLNGIYYPGGTYDPRNNSPYEIENGVVWVPFRGAD--YSLRAVRMKIRPLV 787

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6788	NP_573254.1	FReD	160..356	CDD:238040	84/225 (37%)
Fga	NP_001104518.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	263..420
		Fibrinogen_aC	392..457	CDD:288972	4/11 (36%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	526..555		2/28 (7%)
		FReD	550..786	CDD:238040	85/244 (35%)
		Fib_alpha	51..190	CDD:285864
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2579
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900