DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6788 and Fcna

DIOPT Version :9

Sequence 1:	NP_573254.1	Gene:	CG6788 / 32773	FlyBaseID:	FBgn0030880	Length:	358	Species:	Drosophila melanogaster
Sequence 2:	NP_032021.1	Gene:	Fcna / 14133	MGIID:	1340905	Length:	334	Species:	Mus musculus

Alignment Length:	203	Identity:	79/203 - (38%)
Similarity:	111/203 - (54%)	Gaps:	25/203 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly   153 CPIDGKGGIYKLKIRELPAFEAPCSSNGWLTIQKRYDGAENFDRGWKDYKDGFGRVRGEFFIGLE 217
            |.:|..||                   ||...|:|.||:.:|.|.|..||.|||.:..||::|.:
Mouse   154 CDMDVDGG-------------------GWTVFQRRVDGSIDFFRDWDSYKRGFGNLGTEFWLGND 199

  Fly   218 KVHLMTRQRRHELYIKLGKIDGTTSHAHYDNFELGGEIESYELKSLGRY-NGTAGDSLRPHERQK 281
            .:||:|.....||.:.|....|..|:|.|.:|::..|.|.|:| :||:: .|||||||..|....
Mouse   200 YLHLLTANGNQELRVDLQDFQGKGSYAKYSSFQVSEEQEKYKL-TLGQFLEGTAGDSLTKHNNMS 263

  Fly   282 FTTNDKDNDAYRFNCAADEYGGWWYYDCAKSMLNGKFYKEGRSRNGKTNGILWGSWHNNDWTYSL 346
            |||:|:||||...||||..:|.|||::|.:|.|||: |..| |.....:||.||:...:.::|.:
Mouse   264 FTTHDQDNDANSMNCAALFHGAWWYHNCHQSNLNGR-YLSG-SHESYADGINWGTGQGHHYSYKV 326

  Fly   347 TFVEMMIR 354
              .||.||
Mouse   327 --AEMKIR 332

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6788	NP_573254.1	FReD	160..356	CDD:238040	76/196 (39%)
Fcna	NP_032021.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	47..117
		Collagen	65..106	CDD:189968
		FReD	123..332	CDD:238040	77/201 (38%)
		A domain, contributes to trimerization. /evidence=ECO:0000250	123..162		4/26 (15%)
		B domain, contributes to trimerization. /evidence=ECO:0000250	163..251		33/88 (38%)
		Carbohydrate-binding. /evidence=ECO:0000250\|UniProtKB:O00602	290..292		0/1 (0%)
		P domain. /evidence=ECO:0000250\|UniProtKB:O00602	325..334		4/10 (40%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2579
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000029
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R16943
SonicParanoid	1	1.000	-	-		X25
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	5.840