DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6788 and Fgb

DIOPT Version :9

Sequence 1:	NP_573254.1	Gene:	CG6788 / 32773	FlyBaseID:	FBgn0030880	Length:	358	Species:	Drosophila melanogaster
Sequence 2:	NP_862897.1	Gene:	Fgb / 110135	MGIID:	99501	Length:	481	Species:	Mus musculus

Alignment Length:	384	Identity:	101/384 - (26%)
Similarity:	167/384 - (43%)	Gaps:	93/384 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly    47 RPILDRFAKVNSSDELKNQVNAMSET----------IKDL----QTRIGHKNELLLLQAGQIKDQ 97
            |||....|      ||.|.:.::|:|          :||:    |.::.....::...:..::||
Mouse   111 RPIKSSIA------ELNNNIQSVSDTSSVTFQYLTLLKDMWKKKQAQVKENENVINEYSSILEDQ 169

  Fly    98 SARLNVLIK-----NMKVLRS--ECLNAQAEIKSKDIQIQLSAAKIKQMSNELVTQCSRQDTCPI 155
            ...::..:.     |::||||  |.|.::.:....||..|:...:         |.|:.....|:
Mouse   170 RLYIDETVNDNIPLNLRVLRSILEDLRSKIQKLESDISAQMEYCR---------TPCTVSCNIPV 225

  Fly   156 DG---------KGG----IYKLK-IRELPAFEAPC----SSNGWLTIQKRYDGAENFDRGWKDYK 202
            ..         |||    :|.:: ...:..:...|    .:.||..||.|.||:.:|.|.|..||
Mouse   226 VSGKECEEIIRKGGETSEMYLIQPDTSIKPYRVYCDMKTENGGWTVIQNRQDGSVDFGRKWDPYK 290

  Fly   203 DGFGRVR------------GEFFIGLEKVHLMTRQRRHELYIKLGKIDGTTSHAHYDNFELGGEI 255
            .|||.:.            ||:::|.:|:..:||....||.|::....|....|||..|.:..|.
Mouse   291 KGFGNIATNEDAKKYCGLPGEYWLGNDKISQLTRMGPTELLIEMEDWKGDKVKAHYGGFTVQNEA 355

  Fly   256 ESYELKSLGRYNGTAGDSLRP--------------HERQKFTTNDKDNDAY-----RFNCAADEY 301
            ..|:: |:.:|.||||::|..              |....|:|.|:|||.:     |..|:.::.
Mouse   356 SKYQV-SVNKYKGTAGNALMDGASQLVGENRTMTIHNGMFFSTYDRDNDGWVTTDPRKQCSKEDG 419

  Fly   302 GGWWYYDCAKSMLNGKFYKEG-----RSRNGKTNGILWGSWHNNDWTYSLTFVEMMIRP 355
            |||||..|..:..||::|..|     .|::|..:|::|.:| ...| ||:..:.|.|||
Mouse   420 GGWWYNRCHAANPNGRYYWGGLYSWDMSKHGTDDGVVWMNW-KGSW-YSMRRMSMKIRP 476

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6788	NP_573254.1	FReD	160..356	CDD:238040	72/241 (30%)
Fgb	NP_862897.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	22..81
		Beta-chain polymerization, binding distal domain of another fibrin. /evidence=ECO:0000250	35..37
		Fib_alpha	82..224	CDD:285864	26/127 (20%)
		FReD	227..476	CDD:294064	72/251 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2579
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	166	1.000	Inparanoid score	I4167
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X25
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.950