DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6788 and tnxba

DIOPT Version :9

Sequence 1:	NP_573254.1	Gene:	CG6788 / 32773	FlyBaseID:	FBgn0030880	Length:	358	Species:	Drosophila melanogaster
Sequence 2:	XP_021322558.1	Gene:	tnxba / 100536295	ZFINID:	ZDB-GENE-070103-5	Length:	2285	Species:	Danio rerio

Alignment Length:	433	Identity:	114/433 - (26%)
Similarity:	175/433 - (40%)	Gaps:	99/433 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 TAYLILILSL-------SISTSLANDPQRSFDQNADNPCSAHRIWVWRPILDRFAKVNS------ 58
            |.|.|.:.|:       .:..|:...|....:....|......:.||:|   ..|||:|
Zfish  1853 TTYDITVSSVLDKLESEPVIASITTVPDSPTELKVVNITDTKALLVWKP---SKAKVDSYILSYG 1914

  Fly    59 ---SDELKNQVNAMSETIKDLQTRIGHKNELLLL----QAGQIKDQS----------ARLNVLIK 106
               |..:...|.....:::. |.|..|::.|.::    |..:::..|          .:|.|:..
Zfish  1915 TTKSPNVTITVTLSGSSVEH-QLRALHRSSLYMVKMTSQVNRLQSSSVSTSFTTGSGVKLQVVTP 1978

  Fly   107 NMKVLRSECLNAQA---EIKSKDIQIQLSAAKIKQMSNELVTQ-------CSRQDTCPIDG-KGG 160
            :.....|..::.:|   ..||..:..|||....:.:.|..||.       .....|..||| :.|
Zfish  1979 DEVTFHSAVISWKAPRVAFKSYRLTYQLSEEVKELILNPSVTHYELTGLAAFSNYTVKIDGERDG 2043

  Fly   161 IY------KLKIRELP-AFEAPCS-------------------SNG---------------WLTI 184
            .|      .....:|| .:...||                   .||               |...
Zfish  2044 QYISFVSSDFTTAQLPHPYPTDCSEVQINGMKESGEAEIYPEGKNGEPVRVYCDMETDGGAWTVF 2108

  Fly   185 QKRYDGAENFDRGWKDYKDGFGRVRGEFFIGLEKVHLMTRQRRHELYIKLGKIDGTTSHAHYDNF 249
            |:|.||:.:|.|.|:||..|||.:.|||::|.:.:|.:|..:...|.|.| :....|:.|.|.||
Zfish  2109 QRRMDGSTDFFRSWRDYSKGFGLLSGEFWLGNDVLHTLTSLKAMSLRIDL-RSGNDTAFAQYINF 2172

  Fly   250 ELGGEIESYELKSLGRYNGTAGDSLRPHERQKFTTNDKDNDAYRFNCAADEYGGWWYYDCAKSML 314
            .:..|...|.: .|..|:||||||::.|:.:.|:|.|||.|....:||....|||||.:|.|:.|
Zfish  2173 NISSEANHYAI-DLSGYSGTAGDSMKYHKGRPFSTKDKDPDTLSIHCAKAYMGGWWYKNCYKANL 2236

  Fly   315 NGKF--YKEGRSRNGKTNGILWGSWHNNDWTYSLTFVEMMIRP 355
            ||.:  |.:.:       |::|..|...|  .||.|.||.:||
Zfish  2237 NGLYASYSDNK-------GVVWIDWKGKD--ASLPFTEMKLRP 2270

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6788	NP_573254.1	FReD	160..356	CDD:238040	76/239 (32%)
tnxba	XP_021322558.1	COG3942	596..>913	CDD:332523
		EGF_2	1380..1406	CDD:285248
		fn3	1792..1870	CDD:306538	4/16 (25%)
		fn3	1880..1952	CDD:306538	14/75 (19%)
		fn3	1976..2037	CDD:306538	11/60 (18%)
		FReD	2061..2270	CDD:238040	70/219 (32%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.910