DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6788 and fgl2

DIOPT Version :9

Sequence 1:	NP_573254.1	Gene:	CG6788 / 32773	FlyBaseID:	FBgn0030880	Length:	358	Species:	Drosophila melanogaster
Sequence 2:	XP_002933134.2	Gene:	fgl2 / 100494596	XenbaseID:	XB-GENE-482375	Length:	429	Species:	Xenopus tropicalis

Alignment Length:	441	Identity:	128/441 - (29%)
Similarity:	186/441 - (42%)	Gaps:	105/441 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 MKTAYLILILSLSISTSLANDPQRSFDQNADNPCSAHRIWVWRPILDRFAKVNSSDE-------- 61
            |||...:..|.:..:.....:.:.:..:...|.||.           |.......||
Frog     1 MKTLICLTTLFILAAVHAGTEEESALGEKVGNSCSI-----------RMKNGGKCDEDGNCPYQI 54

  Fly    62 --------LKNQVNAMSETIKDLQTRIGHKNEL------LLLQA--------GQIK------DQS 98
                    |..|...:.:|||::|:.....|.|      ..|||        ||..      ||.
Frog    55 NLPSMTIQLPKQFQLLEKTIKEVQSLKEIVNALKKSCQDCKLQADDTPEKDNGQQNPESTNGDQD 119

  Fly    99 ARLNVLIKNMKVLRSECLNAQAEIKSKDIQI------------QLSAAKIKQMS---NELVTQCS 148
            ..::.|...:|.:.....||:.:|.|...|:            |....|:..:|   |.|..:||
Frog   120 NNIHELQSKVKKMSISLKNARNQINSLQEQLGKMSPINMNTIEQYVDTKMINLSFALNNLDNKCS 184

  Fly   149 RQDTCPI-DGKGGI----------YKL------KIRELP-----AFEAPCS----SNGWLTIQKR 187
              ..||: :....|          ||:      :.|..|     .||..|.    ..||..:|.|
Frog   185 --SNCPVLEANPSIQLLYKDCSDYYKIGKKVDGRYRVTPDEKNKTFEVYCDMESMGGGWTVVQIR 247

  Fly   188 YDGAENFDRGWKDYKDGFGRVRGEFFIGLEKVHLMTRQRRHELYIKLGKIDGTTSHAHYDNFELG 252
            .||:.:|:|.|.:||:|||.:.|||::|.:|:||:|:.....|.|:|....|...:|.||.|.:.
Frog   248 KDGSTSFNRTWNEYKNGFGNLTGEFWLGNDKLHLLTKSTDMILRIELEDFKGNREYAKYDQFYVA 312

  Fly   253 GEIESYELKSLGRYNGTAGDSLR-----PHERQKFTTNDKDNDAY-RFNCAADEYGGWWYYDCAK 311
            .|...|.| ::|.|:|||||:|.     .|:::.|||.|||||.| ..||.:....|||:..|..
Frog   313 NEYLKYRL-TIGGYSGTAGDALHFSKQYNHDQKFFTTPDKDNDRYPSGNCGSYYSSGWWFDACMS 376

  Fly   312 SMLNGKFYKEGRSRNGKTNGILWGSW------HNNDWTYSLTFVEMMIRPR 356
            :.||||:||  ....|..|||.||:|      |.|.:..:..||:|||||:
Frog   377 ANLNGKYYK--NDYKGVRNGIFWGTWTGVSDEHLNSYRQTFKFVKMMIRPK 425

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6788	NP_573254.1	FReD	160..356	CDD:238040	86/232 (37%)
fgl2	XP_002933134.2	Smc	<53..164	CDD:224117	22/110 (20%)
fgl2	XP_002933134.2	FReD	199..425	CDD:238040	85/228 (37%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X25
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.910