DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6788 and tnxb

DIOPT Version :9

Sequence 1:	NP_573254.1	Gene:	CG6788 / 32773	FlyBaseID:	FBgn0030880	Length:	358	Species:	Drosophila melanogaster
Sequence 2:	XP_031747219.1	Gene:	tnxb / 100489649	XenbaseID:	XB-GENE-481849	Length:	2840	Species:	Xenopus tropicalis

Alignment Length:	371	Identity:	93/371 - (25%)
Similarity:	159/371 - (42%)	Gaps:	63/371 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 TAYLILILSLSISTSLANDPQRSFDQNADNP--------CSAHRIWVWRP---ILDRFAKV--NS 58
            |.|...:.||. .:.|::....||..:||.|        .:...:..|:|   :.|.:..|  ..
Frog  2504 TEYYASVQSLH-GSKLSSPTSTSFITSADTPRELLASQITAQSALLTWKPPQVVPDGYRLVYQTH 2567

  Fly    59 SDELKNQV---NAMSETIKDLQTRIGHKNELLLLQAGQIKDQSARLNVLIKNMKV---LRSEC-- 115
            ..|:|..:   |..|.|:..|.....:|.:|..|:..   ..||.::......::   ...:|
Frog  2568 DGEIKELILLANLSSFTLSHLTPSTPYKVQLHALRGA---SSSAPISTSFTTGRIRYPFPRDCWE 2629

  Fly   116 LNAQAEIKSKDIQIQLSAAKIKQMSNELVTQCSRQDTCPIDGKGGIYKLKIRELPAFEAPCSSNG 180
            .:...:::|....|.|..:|    .:.|:..|..:    .||                     .|
Frog  2630 KHMNGDLQSGVFTIYLGGSK----DDPLLVYCDME----TDG---------------------GG 2665

  Fly   181 WLTIQKRYDGAENFDRGWKDYKDGFGRVRGEFFIGLEKVHLMTRQRRHELYIKLGKIDGTTSHAH 245
            |:..|:|.||..:|.|.|:.||:|||.:..||::|...:|.::....:||.:.| :.....::|.
Frog  2666 WIVFQRRIDGRTDFWRNWRQYKEGFGNLTSEFWLGNIALHRLSSLAPYELRVDL-RAGAEAAYAV 2729

  Fly   246 YDNFELGGEIESYELKSLGRYNGTAGDSLRPHERQKFTTNDKDNDAYRFNCAADEYGGWWYYDCA 310
            |::|.:.||.:.:.|: :|.|.|.|||||..|....|:|.|:|.:.....|:....|.|||.:|.
Frog  2730 YEDFRVEGEDKHFRLR-IGAYRGNAGDSLSYHNNMIFSTRDRDAEKRILPCSISYRGAWWYKNCH 2793

  Fly   311 KSMLNGKFYKEGRSRNGKTNGILWGSWHNNDWTYSLTFVEMMIRPR 356
            .:.|||.:     ..|....|:.|.:|  ..:.:|:.|.||.:||:
Frog  2794 YANLNGMY-----GNNKDHQGVNWHTW--KGFEFSIPFTEMKMRPQ 2832

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6788	NP_573254.1	FReD	160..356	CDD:238040	58/195 (30%)
tnxb	XP_031747219.1	EGF_Tenascin	179..206	CDD:376143
		exchanger_TraA	<400..779	CDD:411343
		EGF_Tenascin	799..826	CDD:376143
		fn3	834..913	CDD:394996
		FN3	923..998	CDD:214495
		fn3	1790..1852	CDD:394996
		fn3	1881..1960	CDD:394996
		fn3	1972..2051	CDD:394996
		fn3	2064..2141	CDD:394996
		fn3	2170..2245	CDD:394996
		fn3	2267..2338	CDD:394996
		FN3	2356..2433	CDD:238020
		fn3	2445..2522	CDD:394996	5/18 (28%)
		fn3	2531..2609	CDD:394996	16/80 (20%)
		FReD	2622..2831	CDD:238040	66/246 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000029
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X25
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.910