Protein Alignment mnb and KNS1

DIOPT Version :9

• Sequence 1: NP_728107.2
• Gene: mnb / 32771
• FlyBaseID: FBgn0259168
• Length: 1047
• Species: Drosophila melanogaster
• Sequence 2: NP_013081.1
• Gene: KNS1 / 850641
• SGDID: S000003942
• Length: 737
• Species: Saccharomyces cerevisiae
• Alignment Length: 515
• Identity: 129/515 - (25%)
• Similarity: 218/515 - (42%)
• Gaps: 136/515 - (26%)

  Fly   207 HHSSPSSSSEVRAMQARIP-NHFREPASGPLRKLSVDLIKTYKHINEVYYAKKKRRAQQTQGDDD 270
            |.:||.|:..  |..|.:| ::.::.....|||.:                      .....:..
Yeast   244 HSTSPFSNPP--AQIASLPQSNLKKQIGSSLRKFT----------------------SNGSSESA 284

  Fly   271 SSNKKERKLYNDGYDDDNHDYIIKNGEKFLD--RYEIDSLIGKGSFGQVVKAYDHE-EQCHVAIK 332
            ||||...|...||:      |:.:..:.|..  |:.:..|:|:|:||:|:|..|:: |..:||:|
Yeast   285 SSNKSNFKTDKDGH------YVYQENDIFGSGGRFVVKDLLGQGTFGKVLKCIDNKYEPNYVAVK 343

  Fly   333 IIKNKKPFLNQAQIEVKLLEMMNRADAENKYYIVKLKRHFMWRNHLCLVFELLSYNLYDLLRNTN 397
            :|:....:...|:.|:::|:.:...|.:.::..:.|:..|.::||:|||.:|...::||.:.:..
Yeast   344 VIRAVDRYREAAKTELRILQTILNNDPQGQFQCLLLRECFDYKNHICLVTDLYGRSIYDFMCSNG 408

  Fly   398 FRGVSLNLTRKFAQQLCTALLFLSTPELNIIHCDLKPENILLCNP-------------------- 442
            ......:..:..|:||..::.||.  :|.|||.||||||||:|:.
Yeast   409 IARFPGSHIQAIARQLIRSVCFLH--DLGIIHTDLKPENILICDETHIAQKLPLKTVQSLSKRRR 471

  Fly   443 ----------KRSAIKIVDFGSSCQLGQRIYHY------IQSRFYRSPEVLLGIQYDLAIDMWSL 491
                      |...|||:||||:      |:||      |.:|.||:||::||:.:....|:||:
Yeast   472 EASKGKRKILKNPEIKIIDFGSA------IFHYEYHPPVISTRHYRAPEIVLGLGWSFPCDIWSI 530

  Fly   492 GCILVEMHTGEPLFSGCNEVDQMNKIVEVLGMP-PKYLLDQA-HKTRKFFDKIVAD-GSYVLK-- 551
            .|:|||:..||.|:.....::.|..:..:.|.| |..::|:. :|::.......:| .|.|:|
Yeast   531 ACVLVELVIGESLYPIHENLEHMAMMQRINGTPFPTDIIDKMFYKSKHKLGNSPSDLNSTVIKHF 595

  Fly   552 -----------KNQNGRKYKPPGSRK--------------------LHDILGVETGGP------- 578
                       ||:.|.......|.|                    ..|.|.:....|
Yeast   596 DRKTLSLQWPEKNKRGDTITTEKSMKRVLQSCDRLDIYISKVLKQDYGDSLSINWNLPPEKNWSL 660

  Fly   579 ------GGRRLDEPGHSVSDYLK---------FKDLILRMLDFDPKTRVTPYYALQHNFF 623
                  ..|:......|.:|.|.         |.||:.:|.:|||..|:|...||.|.:|
Yeast   661 INSKLAWKRQTHSSSSSTTDELDKETFLFWYWFIDLLRKMFEFDPTKRITAKDALDHEWF 720

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mnb	NP_728107.2	PKc_DYRK1	289..628	CDD:271128	112/432 (26%)
		S_TKc	303..623	CDD:214567	108/414 (26%)
KNS1	NP_013081.1	PKc_CLK	298..720	CDD:271036	111/435 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157345193
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0667
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.740