Protein Alignment mnb and Hipk3

DIOPT Version :9

• Sequence 1: NP_728107.2
• Gene: mnb / 32771
• FlyBaseID: FBgn0259168
• Length: 1047
• Species: Drosophila melanogaster
• Sequence 2: XP_038961862.1
• Gene: Hipk3 / 83617
• RGDID: 619884
• Length: 1213
• Species: Rattus norvegicus
• Alignment Length: 1038
• Identity: 243/1038 - (23%)
• Similarity: 371/1038 - (35%)
• Gaps: 303/1038 - (29%)

  Fly   169 VDAAQGSGSG----------------GGRQRHAPLYGRFVDAEDLPATHRDVMHHHSSPSSSSEV 217
            |.|||...:|                ||.||..           |.....::.:|..:.....|:
  Rat    94 VIAAQAQQAGVEAPRAVVWRNRLHFLGGPQRCG-----------LKRKSEELDNHSGAMQIVDEL 147

  Fly   218 RAMQARIPNHFREPASGPLRKLSVDLIKTYKHINEVYYAKKKRRAQQTQGDDDSSNKKERKLYND 282
            ..:.|.:..:...|.:                   |..|....:...|.|:.|
  Rat   148 SILPAMLQTNMGNPVT-------------------VVTATTGSKQNCTSGEGD------------ 181

  Fly   283 GYDDDNHDYI--IKNGEKFLDRYEIDSLIGKGSFGQVVKAYDHEEQCHVAIKIIKNKKPFLNQAQ 345
             |....|:.:  :||      .||:...:|:|:||||||.:.......|||||:||...:..|.|
  Rat   182 -YQLVQHEVLCSVKN------TYEVLDFLGRGTFGQVVKCWKRGTNEIVAIKILKNHPSYARQGQ 239

  Fly   346 IEVKLLEMMNRADAENKYYIVKLKRHFMWRNHLCLVFELLSYNLYDLLRNTNFRGVSLNLTRKFA 410
            |||.:|..::..:|: :|..|:....|..|||.|||||:|..||||.|:...|..:.|.:.|...
  Rat   240 IEVSILARLSTENAD-EYNFVRAYECFQHRNHTCLVFEMLEQNLYDFLKQNKFSPLPLKVIRPVL 303

  Fly   411 QQLCTALLFLSTPELNIIHCDLKPENILLCNPKRS--AIKIVDFGSSCQLGQRIYH-YIQSRFYR 472
            ||:.|||..|.:  |.:||.|||||||:|.:|.|.  .:|::||||:..:.:.:.. |:|||:||
  Rat   304 QQVATALKKLKS--LGLIHADLKPENIMLVDPVRQPYRVKVIDFGSASHVSKTVCSTYLQSRYYR 366

  Fly   473 SPEVLLGIQYDLAIDMWSLGCILVEMHTGEPLFSGCNEVDQMNKIVEVLGMPPKYLLDQAHKTRK 537
            :||::||:.:..|||||||||::.|:..|.||:.|..|.||:..|.:..|:|.:.||:...|:.:
  Rat   367 APEIILGLPFCEAIDMWSLGCVIAELFLGWPLYPGALEYDQIRYISQTQGLPGEQLLNVGTKSTR 431

  Fly   538 FF--DKIVADGSYVLK-----------KNQNGRKYKPPGSRKLHDILGVETGGPGGRRLDEPGHS 589
            ||  :..::...:.||           |::..|||.   ...|.||:.|.|      .:|..|..
  Rat   432 FFCRETDMSHSGWRLKTLEEHEAETGMKSKEARKYI---FNSLDDIVHVNT------VMDLEGSD 487

  Fly   590 V----SDYLKFKDLILRMLDFDPKTRVTPYYALQHNF--FKRTAD-------------------- 628
            :    :|..:|..|:.:||..|...|:||...|.|.|  .|...|
  Rat   488 LLAEKADRREFVSLLKKMLLIDADLRITPIETLNHPFVSMKHLLDFPHSSHVKSCFHIMDICKSP 552

  Fly   629 ---EATNTSGAGATANAGAGGSGSSGAGGSSGGGVGGGLGASNSSSGAVSSSSAAAPTAATAAAT 690
               |..|.|.........:.|:.:..|..:.       :|...|.:...|:.|.........|.|
  Rat   553 SSCETNNHSKMSLLRPVASNGTAALAANFTK-------VGTLRSQALTTSAHSVVHHGIPLQAGT 610

  Fly   691 AAGSSG--------------SGSSVGGG---SSAAQQQQAMPLPLPLPLPLPPLAGPGGAS---- 734
            |....|              .|.....|   |.:.:....:||....|...|....||..|
  Rat   611 AQFGCGDAFHQTLIICPPAIQGIPAAHGKPTSYSIRVDNTVPLVTQAPAVQPLQIRPGVLSQQTW 675

  Fly   735 DGQCHGLLMHS-------------------VAANAMNNFSALSLQSNAH----PPPSLAN----S 772
            .|:...:|:.:                   ..:..:.::..:...||.:    |||.|.|    |
  Rat   676 SGRTQQMLIPAWQQVTPMAPAAATLTSEGMAGSQRLGDWGKMIPHSNHYNSVMPPPLLTNQITLS 740

  Fly   773 HHSTNSLGSLNHI---SPGSTG----CHNNN--------------------SNS-SNNNTRHSRL 809
            .....|:| :.|:   .|.:|.    |.|..                    ||| .|.|..||..
  Rat   741 APQPISVG-IAHVVWPQPATTKKNKLCQNRGILVKLMEWEPGREEINAFRWSNSLQNTNVPHSAF 804

  Fly   810 YGSNMVNMVGHHNSG----------SSNNHNSISYPHAMECDPPQMPPPPPNGHGRMRVPAIMQL 864
            ....::       ||          :.:||.|                   .|..|
  Rat   805 ISPKII-------SGKEVEEVSCVETQDNHTS-------------------EGEAR--------- 834

  Fly   865 QPNSYAPNSVPYYGNMSSSSVAAAAAAAAAAASHLMMTDS-----SVISASA-AGGGQGGGNPG- 922
                          ....:||...::.:......:::.||     |||:.|: ....:....|.
  Rat   835 --------------TCHEASVRQDSSVSDKQRQTIIIADSPSPAVSVITISSDTDDEETSPRPSL 885

  Fly   923 ------------QNPVTPSAAAFLFPSQPAGTLYGTALGSLSDLPLPMPLPMSVPLQLPPSSSSS 975
                        |:.:.......|  |.|..||..::.|..|..|...|..||...|   .|...
  Rat   886 RECKGSLDCEACQSTLNIDRMCSL--SSPDSTLSTSSSGQSSPSPCKRPNSMSDDEQ---ESGCE 945

  Fly   976 VSSGSASVGSGGVGVGVVGQRRHITGPAAQVGISQSVGSGSSGSATGASSSDASSSS--PMVG 1036
            ...||.:..|.|          |.:..|....:..:..:...|:..|..:..|.|::  |.||
  Rat   946 TVDGSPTSDSSG----------HDSPFAESSFVEDTPQNPELGTCAGTEAKPALSTAVEPPVG 998

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mnb	NP_728107.2	PKc_DYRK1	289..628	CDD:271128	132/362 (36%)
		S_TKc	303..623	CDD:214567	128/341 (38%)
Hipk3	XP_038961862.1	STKc_HIPK3	196..525	CDD:271131	127/340 (37%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0667
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810