Protein Alignment mnb and clk2b

DIOPT Version :9

• Sequence 1: NP_728107.2
• Gene: mnb / 32771
• FlyBaseID: FBgn0259168
• Length: 1047
• Species: Drosophila melanogaster
• Sequence 2: NP_001070219.1
• Gene: clk2b / 767784
• ZFINID: ZDB-GENE-060929-1126
• Length: 500
• Species: Danio rerio
• Alignment Length: 539
• Identity: 141/539 - (26%)
• Similarity: 236/539 - (43%)
• Gaps: 117/539 - (21%)

  Fly   142 SSSSSSRMKAERALYYTMSAYGSSGGSVDAAQGSGSGGGRQRHAPLYGRFVDAEDLPATHRDVMH 206
            |.|.|..|:.||......|...|...|:       |...|:|                 ||:..|
Zfish    15 SRSRSRHMRYERHRRRRRSRTRSRSRSI-------SSRSRRR-----------------HRERRH 55

  Fly   207 HHSSPSSSSEVRAMQARIPNHFREPASGPLRKLSVDLIKTYKH-------INEVYYAKKKRRAQQ 264
            ..||...||            :::| ||..|:.|....:..:.       ..:.|:...:.|..:
Zfish    56 RDSSSRRSS------------YQQP-SGERRRSSRRYCRDEREEFDRDYTFTDGYFRHTRSRDHR 107

  Fly   265 TQGDDDSSNKKER-----------KLYNDG----------YDDDNHDYIIKNGEKFLDRYEIDSL 308
            |:.|.....::.|           :.|:..          .||:....|.:.|:...|||||...
Zfish   108 TERDSGRRRRRRRTRTRTRTRSRTRSYSQSRSISSKAWAVKDDEEGHLIYRAGDVLQDRYEITQT 172

  Fly   309 IGKGSFGQVVKAYDHEE-QCHVAIKIIKNKKPFLNQAQIEVKLLEMMNRADAENKYYIVKLKRHF 372
            :|:|:||:||:..||:. ...:|:|||||.:.:...|::|:.:||.:|:.|.|||...|::...|
Zfish   173 LGEGTFGKVVECVDHQRGGSRIALKIIKNVEKYKEAARLEINVLEKINQRDPENKNLCVQMLDWF 237

  Fly   373 MWRNHLCLVFELLSYNLYDLLRNTNFRGVSLNLTRKFAQQLCTALLFLSTPELNIIHCDLKPENI 437
            .:..|:||.||||..:.:|.::..|:...|::..|..|.|:|.|:.||...:|.  |.|||||||
Zfish   238 DYHGHMCLSFELLGLSTFDFMKENNYLPYSISQVRHMAYQICLAVKFLHDNKLT--HTDLKPENI 300

  Fly   438 L--------LCNPKR---------SAIKIVDFGSSCQLGQRIYHYIQSRFYRSPEVLLGIQYDLA 485
            |        |.|.::         :|::||||||:....:.....:.:|.||:|||:|.:.:...
Zfish   301 LFVSSDYSVLYNAEKKRDERSVNSTAVRIVDFGSATFDHEHHSSIVSTRHYRAPEVILELGWSQP 365

  Fly   486 IDMWSLGCILVEMHTGEPLFSGCNEVDQMNKIVEVLGMPPKYLLDQAHKTRKFF------DKIVA 544
            .|:||:||||.|.:.|..|:...:..:.:..:..:.|..|..::.:..|.:.|:      |:..:
Zfish   366 CDVWSIGCILFEFYCGYTLYQTHDNREHLAMMERIHGPVPSRMIRKTRKQKYFYRGRLDWDESTS 430

  Fly   545 DGSYVLKKNQNGRKYKPPGSRKLHDILGVETGGPGGRRLDEPGHSVSDYLKFKDLILRMLDFDPK 609
            .|.||.:..:..|:|....|                          .|:.:|.||:..:|:::|:
Zfish   431 AGRYVRENCRPLRRYMLCES--------------------------EDHHQFFDLLEGLLEYEPE 469

  Fly   610 TRVTPYYALQHNFFKRTAD 628
            .|::...||:|.||....|
Zfish   470 QRLSLSAALRHPFFSLLRD 488

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mnb	NP_728107.2	PKc_DYRK1	289..628	CDD:271128	108/362 (30%)
		S_TKc	303..623	CDD:214567	102/343 (30%)
clk2b	NP_001070219.1	PKc_like	154..483	CDD:304357	106/356 (30%)
		S_TKc	167..483	CDD:214567	102/343 (30%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0667
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810