Protein Alignment mnb and Clk2

DIOPT Version :9

• Sequence 1: NP_728107.2
• Gene: mnb / 32771
• FlyBaseID: FBgn0259168
• Length: 1047
• Species: Drosophila melanogaster
• Sequence 2: XP_008759408.1
• Gene: Clk2 / 365842
• RGDID: 1359711
• Length: 540
• Species: Rattus norvegicus
• Alignment Length: 650
• Identity: 161/650 - (24%)
• Similarity: 261/650 - (40%)
• Gaps: 179/650 - (27%)

  Fly    35 GSFSSSIITSSSSSLN----H-------HPHNGHHN--------HHHPPHYINYLAQIGCQHRVR 80
            |:.|.:::|.....|.    |       ||...|.:        |.|      |.::...:.|.|
  Rat     8 GNISHTLVTCRELWLRPEGLHGAMFEMPHPRRYHSSERGSRGSYHEH------YRSRKHKRRRSR 66

  Fly    81 NWPTNGNQDQADDDDAGHQIISKFLPKSAWDTVLLDVKRDVDEDGDRDRDRVDGNVLMVQGSSSS 145
            :|.:..::                            .:|...||....|.| .|.:|    |:||
  Rat    67 SWSSTSDR----------------------------TRRRRREDSYHVRSR-SGYLL----SNSS 98

  Fly   146 SSRMKAERALY-------YTMSAYGSSGGSVDAAQGSGSGGGRQRHAPLYGRFVDAEDLPATHRD 203
            .....::|.||       |..:.|....|  :|...:..     ||:..|            ||:
  Rat    99 YDDHSSDRRLYDRRYCGSYRRNDYSRDRG--EAYYDTDF-----RHSYEY------------HRE 144

  Fly   204 VMHHHSSPSSSSEVRAMQARIPNHFREPASGPLRKLSVDLIKTYKHINEVYYAKKKRRAQQTQGD 268
            ...:.|..||.              |:|                         :::||..:|...
  Rat   145 NSSYRSQRSSR--------------RKP-------------------------RRRRRRSRTFSH 170

  Fly   269 DDSSNKKERKLYNDGYDDDNHDYIIKN-GEKFLDRYEIDSLIGKGSFGQVVKAYDHEE-QCHVAI 331
            ..|.:...|.   ...:||...::|.: |:...:||||.|.:|:|:||:||:..||.. ...||:
  Rat   171 SSSQHSSRRA---KSVEDDAEGHLIYHVGDWLQERYEIVSTLGEGTFGRVVQCVDHRRGGARVAL 232

  Fly   332 KIIKNKKPFLNQAQIEVKLLEMMNRADAENKYYIVKLKRHFMWRNHLCLVFELLSYNLYDLLRNT 396
            |||||.:.:...|::|:.:||.:|..|.:||...|::...|.:..|:|:.||||..:.:|.|::.
  Rat   233 KIIKNVEKYKEAARLEINVLEKINEKDPDNKNLCVQMFDWFDYHGHMCISFELLGLSTFDFLKDN 297

  Fly   397 NFRGVSLNLTRKFAQQLCTALLFLSTPELNIIHCDLKPENILLCNP-----------------KR 444
            |:....::..|..|.|||.|:.||...:|.  |.||||||||..|.                 |.
  Rat   298 NYLPYPIHQVRHMAFQLCQAVKFLHDNKLT--HTDLKPENILFVNSDYELTYNLEKKRDERSVKS 360

  Fly   445 SAIKIVDFGSSCQLGQRIYHYIQSRFYRSPEVLLGIQYDLAIDMWSLGCILVEMHTGEPLFSGCN 509
            :|:::|||||:....:.....:.:|.||:|||:|.:.:....|:||:|||:.|.:.|..||...:
  Rat   361 TAVRVVDFGSATFDHEHHSTIVSTRHYRAPEVILELGWSQPCDVWSIGCIIFEYYVGFTLFQTHD 425

  Fly   510 EVDQMNKIVEVLGMPPKYLLDQAHKTRKFF------DKIVADGSYVLKKNQNGRKYKPPGSRKLH 568
            ..:.:..:..:||..|..::.:..|.:.|:      |:..:.|.||.:..:..|:|....:...|
  Rat   426 NREHLAMMERILGPVPSRMIRKTRKQKYFYRGRLDWDENTSAGRYVRENCKPLRRYLTSEAEDHH 490

  Fly   569 DILGVETGGPGGRRLDEPGHSVSDYLKFKDLILRMLDFDPKTRVTPYYALQHNFFKRTADEATNT 633
            .:.                          |||..||:::|..|:|...||||.||.....|..||
  Rat   491 QLF--------------------------DLIENMLEYEPAKRLTLGEALQHPFFACLRTEPPNT 529

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mnb	NP_728107.2	PKc_DYRK1	289..628	CDD:271128	110/363 (30%)
		S_TKc	303..623	CDD:214567	105/343 (31%)
Clk2	XP_008759408.1	PKc_CLK2	190..519	CDD:271117	108/356 (30%)
		S_TKc	203..519	CDD:214567	105/343 (31%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0667
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810