Protein Alignment mnb and pom2

DIOPT Version :9

• Sequence 1: NP_728107.2
• Gene: mnb / 32771
• FlyBaseID: FBgn0259168
• Length: 1047
• Species: Drosophila melanogaster
• Sequence 2: NP_593081.2
• Gene: pom2 / 2542326
• PomBaseID: SPAC16C9.07
• Length: 836
• Species: Schizosaccharomyces pombe
• Alignment Length: 657
• Identity: 202/657 - (30%)
• Similarity: 302/657 - (45%)
• Gaps: 136/657 - (20%)

  Fly    46 SSSLNHHPHNGHHNHHHPPHYINYLAQIGCQHRVRNWPTNGNQDQADDDDAGHQIISKFLPKS-- 108
            ||..|.:.:......|....:.:..:.|     |....|.|...:..||.|  ::.|:..|.:
pombe   213 SSETNKYEYPQQSKFHECSQFASPRSSI-----VNGPRTLGKNSKRADDTA--RMASRMKPSNFN 270

  Fly   109 ----------AWDTVLLDVKRDVDEDGDRD---------RDRVDGNVLMVQGSSSSSSRMKAERA 154
                      |..:..|..:||.|...|.:         .:|....:..:.|.|.|::
pombe   271 NNIQSSSYGHASQSTKLTSQRDNDHQKDLNFSPYKSIPLNNRPYSPMSEIVGFSGSTT------- 328

  Fly   155 LYYTMSAYGS--SG------------GSVDAAQGSGSGGGRQRHAPLYGRFVDAEDLPATHRDVM 205
               .:..||:  ||            ||..::..|.|...|...||  |..|.||
pombe   329 ---PLDTYGNRPSGKKFNKNSKFRPPGSTISSYSSASTLRRLPRAP--GSKVHAE---------- 378

  Fly   206 HHHSSPSSSSEVRAMQARIPNHFREPASGPLRKLSVDLI-------KTYKHINEVYYAKKKRR-- 261
            ..:|:.:|...:||::..:.|  ..|.|........||:       .|.|.:.||...|:.|.
pombe   379 RQNSTFNSGISLRALRKEMGN--TAPVSSNQLLKDADLVMENLSTRNTEKVLREVNILKRLRESC 441

  Fly   262 -AQQTQGDDDSSNKKER--------------KLYNDG--------------------YDDDNHDY 291
             |...:..|....:|.|              |:|..|                    :||||.||
pombe   442 VAITAKSYDTLDERKIRSLTTFEYLEIKNFQKIYFTGSENCQKLSKQIPLDECNEALFDDDNGDY 506

  Fly   292 IIKNGEKFLDRYEIDSLIGKGSFGQVVKAYDHEEQCHVAIKIIKNKKPFLNQAQIEVKLLEMMNR 356
            ....|:..|.||||...:||||||||:|..||:....||||:|||::.|..|..:||.:|:.:..
pombe   507 KAIQGDHLLYRYEIIDTVGKGSFGQVLKCIDHKRGQVVAIKVIKNRQKFHGQTLVEVGILKRLCE 571

  Fly   357 ADAENKYYIVKLKRHFMWRNHLCLVFELLSYNLYDLLRNTNFRGVSLNLTRKFAQQLCTALLFLS 421
            ||..:|..:::...||.:|.|||:|.|||..||:|::|..|::|:.|.:.:.||.|...||..|.
pombe   572 ADPADKNNVIRYLSHFDFRGHLCIVTELLGSNLFDVIRENNYKGLPLIVVKSFALQGLQALRLLQ 636

  Fly   422 TPELNIIHCDLKPENILLCNPKRSAIKIVDFGSSCQLGQRIYHYIQSRFYRSPEVLLGIQYDLAI 486
            ..  |||||||||||:||.:|.::.||::||||||...:::|.|:||||||:||::||::|...|
pombe   637 GQ--NIIHCDLKPENLLLSHPLKARIKLIDFGSSCFYNEKVYTYLQSRFYRAPEIILGLEYGKEI 699

  Fly   487 DMWSLGCILVEMHTGEPLFSGCNEVDQMNKIVEVLGMPPKYLLDQAHKTRKFFDKIVADGS-YVL 550
            |:||.||||.|:.||.|||.|.||.:|:..|:||||.||..|:..:.:::.:||   ::|. :.:
pombe   700 DIWSFGCILAELFTGVPLFPGGNETEQLGYIMEVLGPPPMALIRNSTRSKAYFD---SEGKPHPI 761

  Fly   551 KKNQNGRKYKPPGSRKLHDILGVETGGPGGRRLDEPGHSVSDYLKFKDLILRMLDFDPKTRVTPY 615
            ..:.|  :...|.:|....:|..:..                  .|.|.:.:.|.:|||.|:|..
pombe   762 TDSHN--RLLVPSTRTFSQLLNTKQA------------------SFLDFLSKCLKWDPKDRITVD 806

  Fly   616 YALQHNF 622
            .||||.|
pombe   807 SALQHEF 813

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mnb	NP_728107.2	PKc_DYRK1	289..628	CDD:271128	138/335 (41%)
		S_TKc	303..623	CDD:214567	133/321 (41%)
pom2	NP_593081.2	PKc_DYRK	504..814	CDD:271112	138/335 (41%)
		S_TKc	518..814	CDD:214567	133/321 (41%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0667
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R968
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	4	3.800