Protein Alignment mnb and prp4

DIOPT Version :10

• Sequence 1: NP_728107.2
• Gene: mnb / 32771
• FlyBaseID: FBgn0259168
• Length: 1047
• Species: Drosophila melanogaster
• Sequence 2: NP_588261.1
• Gene: prp4 / 2539312
• PomBaseID: SPCC777.14
• Length: 477
• Species: Schizosaccharomyces pombe
• Alignment Length: 480
• Identity: 148/480 - (30%)
• Similarity: 220/480 - (45%)
• Gaps: 95/480 - (19%)

  Fly   218 RAMQARIPNHFREPASG------PLRKL--SVDLIKTYKHINEVYYAKKKRRAQQTQGDDDSSNK 274
            |..:..|...:::..:|      |.:||  .||.:.|.|.|..|  .|.|..|.:.:.:.:.||.
pombe    16 RKRRLEILKKYQQTGNGHSDLSIPEKKLKEDVDQVSTTKPIEAV--PKMKTNASKIEINKEGSNS 78

  Fly   275 KER------------------------------------KLYN----------------DGYDDD 287
            ..:                                    |..|                |.:||.
pombe    79 NTKLDVTNSTTSDSPSIKSSVQIEDTEDDMFADSPSPSVKRQNTGKGISTLTRSFADMQDNWDDI 143

  Fly   288 NHDYIIKNGEKFLDRYEIDSLIGKGSFGQVVKAYDHEEQCHVAIKIIKNKKPFLNQAQIEVKLLE 352
            ...|.:...|:...||.:.|.:|||.|..||.|.|.......|||||:|.:....:...||.:||
pombe   144 EGYYKVVLMEELDSRYIVQSNLGKGMFSTVVSALDRNRNQTFAIKIIRNNEVMYKEGLKEVSILE 208

  Fly   353 MMNRADAENKYYIVKLKRHFMWRNHLCLVFELLSYNLYDLL----RNTNFRGVSLNLTRKFAQQL 413
            .:..||.|.|.:|:..:||||.:||||:|||:||.||.|:|    ||.   |:|:...|.:|.|:
pombe   209 RLQAADREGKQHIIHYERHFMHKNHLCMVFEMLSLNLRDILKKFGRNV---GLSIKAVRLYAYQM 270

  Fly   414 CTALLFLSTPELNIIHCDLKPENILLCNPKRSAIKIVDFGSSCQLGQ-RIYHYIQSRFYRSPEVL 477
            ..||..|.  :.|:||.|:||:|:|: |.||:.:||.|.||:....: .|..|:.|||||:||::
pombe   271 FMALDLLK--QCNVIHSDIKPDNMLV-NEKRNILKICDLGSASDASENEITPYLVSRFYRAPEII 332

  Fly   478 LGIQYDLAIDMWSLGCILVEMHTGEPLFSGCNEVDQMNKIVEVLGMPPKYLLDQAHKTRKFFDKI 542
            ||..|...||.||:||.|.|::||:.||.|......:..::|..|.....:|.::......||
pombe   333 LGFPYSCPIDTWSVGCSLYELYTGQILFPGRTNNQMLRYMMECKGKFSHKMLKRSQFLNDHFD-- 395

  Fly   543 VADGSYVL-----KKNQNGRKYKPPGSRKLHDILGVETGGPGGRRLDE-PGHSVSDYL---KFKD 598
             ||.:::.     ..||..|| ....|:...||..         ||.| |..:..:::   :..|
pombe   396 -ADFNFIQIDHDPITNQETRK-PVKFSKPTKDIRS---------RLKEVPTSTDEEFIIRQELMD 449

  Fly   599 LILRMLDFDPKTRVTPYYALQHNFF 623
            |:.:.|:.:|:.||.|..||:|.||
pombe   450 LLEKCLELNPEKRVPPEVALKHPFF 474

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mnb	NP_728107.2	PKc_DYRK1	289..628	CDD:271128	126/349 (36%)
prp4	NP_588261.1	STKc_PRP4	158..474	CDD:271037	122/334 (37%)