Protein Alignment mnb and C36B7.2

DIOPT Version :10

• Sequence 1: NP_728107.2
• Gene: mnb / 32771
• FlyBaseID: FBgn0259168
• Length: 1047
• Species: Drosophila melanogaster
• Sequence 2: NP_509198.2
• Gene: C36B7.2 / 183254
• WormBaseID: WBGene00016465
• Length: 446
• Species: Caenorhabditis elegans
• Alignment Length: 433
• Identity: 112/433 - (25%)
• Similarity: 195/433 - (45%)
• Gaps: 60/433 - (13%)

  Fly   218 RAMQARIPNHFRE----PASGP-LRKLSV-----DLIKTYKHINEVYYAKKKRRAQQTQGDDDSS 272
            |.::.|..||..:    |...| |...|:     .|:..::.|....|.|....:...:......
 Worm    20 RIVRKRAQNHCVDQTVYPNENPGLSPSSIFNGYSHLLSPFEKIEVKKYGKIYALSMNPETLKAPE 84

  Fly   273 NKKERKLYNDGYDDDNHDYIIKNGEKFLDRYEIDSLIGKGSFGQVVKAYDHEEQCHVAIKIIKNK 337
            |..|:..:..|     ..|.:|..|....||.||.:||:|.:|.|.:|.|.:.:..|||:::...
 Worm    85 NAIEKDFFEMG-----SIYKMKKDEHIGYRYTIDKVIGQGCYGVVGEATDGKTKQKVAIRMVSKL 144

  Fly   338 KPFLNQAQIEVKLLEMMNRADAENKYYIVKLKRHFMWRNHLCLVFELLSYNLYDLLRNTNFRGVS 402
            .|.:.:   |.:::..::..|.::.:..|::..:.::|....:|.:|...::...::..:..|::
 Worm   145 APRIYR---ETEMIMYISSIDPDHTFDCVRMLDYNVFRGFHYVVTDLFDTSVKKYIKEHHPNGIA 206

  Fly   403 LNLTRKFAQQLCTALLFLSTPELNIIHCDLKPENIL--LCNPKRSAIKIVDFGSSCQLGQRIYH- 464
            |.......:::...|:||.  |.||:|.|||||||:  |.||  :.:|:.|||.|  ...:.||
 Worm   207 LENVAAMGRKILKGLVFLH--EHNIVHGDLKPENIMLNLANP--NDVKLGDFGLS--RFAKPYHD 265

  Fly   465 --YIQSRFYRSPEVLLGIQYDLAIDMWSLGCILVEMHTGEPLFSGCNEVDQMNKIVEVLGMPPKY 527
              ..||.|||:||..:..:|:.|.||||.||.:.||.:|:...:|.|..||...:.||:.:||..
 Worm   266 HVQCQSMFYRAPEAFVRGRYNGATDMWSFGCTVAEMVSGKIFLAGDNCDDQFYLMQEVINIPPPV 330

  Fly   528 LLDQAHKTRKFFDK--------IVADG----SYVLKKNQNGRKYKPPGSRKLHDILGVETGGPGG 580
            ..|..:....||..        ::.|.    |::..|..:.||.  ||:..:....
 Worm   331 FFDTFYTNYYFFSTLKEAPKHIVITDHGPIVSFIYTKAADHRKI--PGATPIGSFF--------- 384

  Fly   581 RRLDEPGHSVSDYLKFKDLILRMLDFDPKTRVTPYYALQHNFF 623
                    :.::...|.:.||::..:.|.:|:|...||.|.||
 Worm   385 --------TKTEQKPFNNFILKVFKWMPASRITAKQALDHPFF 419

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mnb	NP_728107.2	PKc_DYRK1	289..628	CDD:271128	97/352 (28%)
C36B7.2	NP_509198.2	Protein Kinases, catalytic domain	98..419	CDD:473864	95/348 (27%)