Protein Alignment mnb and C36B7.1

DIOPT Version :10

• Sequence 1: NP_728107.2
• Gene: mnb / 32771
• FlyBaseID: FBgn0259168
• Length: 1047
• Species: Drosophila melanogaster
• Sequence 2: NP_509199.1
• Gene: C36B7.1 / 183253
• WormBaseID: WBGene00016464
• Length: 450
• Species: Caenorhabditis elegans
• Alignment Length: 384
• Identity: 108/384 - (28%)
• Similarity: 166/384 - (43%)
• Gaps: 60/384 - (15%)

  Fly   265 TQGDDDSSNKKERKLYNDG-YDDDNHDYIIKNGEKFLDRYEIDSLIGKGSFGQVVKAYDHEEQCH 328
            |.||..|.|:...:|   | :...|..|..|.|:....||.||.::..|.:.||.:..|.:....
 Worm    95 TVGDYGSKNQTNHEL---GIFTLPNGSYCFKEGDHISYRYSIDEVLSSGYYAQVFRCTDKKTDKK 156

  Fly   329 VAIKIIKNKKPFLNQAQIEVKLLEMMNRADAENKYYIVKLKRHFMWRNHLCLVFELLSYNLYDLL 393
            |.|| :||:.  |:....|..:|..:::.:.:|....|::..:..:|.|..:|.|....:|...|
 Worm   157 VCIK-LKNRN--LSTTYEETIILLRIHQLNRQNNSNCVRMLDYDHFRGHHFIVLENYQTDLASYL 218

  Fly   394 RNTNFRGVSLNLTRKF---AQQLCTALLFLSTPELNIIHCDLKPENILLCNPKRSAIKIVDFGSS 455
                 .|.|....|::   .:.:...|.||.  :..|||.||||.|:||....|:.:|:.|||.|
 Worm   219 -----CGRSKLTPREYIPMIKSIVHGLKFLH--QNKIIHGDLKPANVLLNEWNRNNLKLTDFGLS 276

  Fly   456 CQLGQ-RIYHYIQSRFYRSPEVLLGIQYDLAIDMWSLGCILVEMHTGEPLFSGCNEVDQMNKIVE 519
            ..:.| ..:...|:.:|::|||....:..:.||:|||||:..|:..|.|||.|.|..||...|.|
 Worm   277 TFVNQGPFFRDYQTLYYKAPEVFCQGKVSVEIDIWSLGCVAAEIVRGTPLFVGDNYFDQFALIQE 341

  Fly   520 VLGMPPKYLLDQ---AHK--TRKFFDK--------------IVADGSYVLKKNQNGRKYKPPGSR 565
            ..|.|.:.|.:.   .|:  |..||.:              :..:..|.|.....    |||.:.
 Worm   342 FFGKPSRKLFNTWGGIHQFYTEYFFPRHCFEWLNPFNGDRTMEIEPHYKLAHPSR----KPPLTS 402

  Fly   566 KLHDILGVETGGPGGRRLDEPGHSVSDYLKF-KDLILRMLDFDPKTRVTPYYALQHNFF 623
            .|...|      |||.:            || ...::|..::||..|:...:.|.|.||
 Worm   403 SLVSKL------PGGNQ------------KFLARFLMRCFEWDPTERIKSSFILNHPFF 443

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mnb	NP_728107.2	PKc_DYRK1	289..628	CDD:271128	100/359 (28%)
C36B7.1	NP_509199.1	Protein Kinases, catalytic domain	117..443	CDD:473864	98/357 (27%)