DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6769 and LOC561361

DIOPT Version :9

Sequence 1:	NP_001259663.1	Gene:	CG6769 / 32770	FlyBaseID:	FBgn0030878	Length:	409	Species:	Drosophila melanogaster
Sequence 2:	XP_021331110.1	Gene:	LOC561361 / 561361	-ID:	-	Length:	952	Species:	Danio rerio

Alignment Length:	292	Identity:	56/292 - (19%)
Similarity:	91/292 - (31%)	Gaps:	92/292 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 FTCLNCDARFASADVQRNHYKTDWHRYNLKRRVAQLPPVTAEEFQQRVLSARSATDAALEEQNLS 68
            |||..|..||..:.....|.::.                |.|:........||.:.::...|::.
Zfish   532 FTCTQCGNRFNCSSHLNRHMRSH----------------TGEKPFTCTQCGRSFSCSSNLYQHMI 580

  Fly    69 VY-------CHACRRQFASQKAHDNHLNSRKHKELLARFEREQMTASGGSASTATSVCTRSVVEQ 126
            ::       |..|.:.|    :...|||  :|..:....:....:..|.|.|.::|:.....:..
Zfish   581 IHTGEKPYTCTQCGKSF----SQSTHLN--QHMRIHTGEKPFTCSRCGKSFSQSSSLNQHIRIHT 639

  Fly   127 RPHPALAAAAAGKGRLAFAERVVKANNDEEMVDEDDDDFEDIEEEEVDSDEWDKIPENPLTERDC 191
            ...| ......||     :.|.....|...|:..:                     |.|.|
Zfish   640 GEKP-FTCTQCGK-----SYRRSSTLNKHMMIHTE---------------------EKPFT---- 673

  Fly   192 LFCTHASEDLVENL---KHMSVAHSFFIPDTEYCTDIE-----------GLLYYLGEKVANYFIC 242
              ||...:...::.   |||.: |:...|.|  ||...           .:..:.|||.   |.|
Zfish   674 --CTQCGKSFSQSSYLHKHMRI-HTGEKPFT--CTQCGKSFSQSSSLKLHIRVHTGEKP---FTC 730

  Fly   243 LFCNDRGKTFYSLDAVRKHMIDKGHCQMLHEG 274
            ..|   ||:|....::..||       |:|.|
Zfish   731 TLC---GKSFSQSSSLNLHM-------MIHTG 752

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6769	NP_001259663.1	C2H2 Zn finger	6..28	CDD:275371	5/21 (24%)
		zf-C2H2_jaz	70..94	CDD:288983	6/30 (20%)
		C2H2 Zn finger	71..93	CDD:275371	6/21 (29%)
		zf-C2H2_2	191..290	CDD:289522	24/98 (24%)
LOC561361	XP_021331110.1	C2H2 Zn finger	58..78	CDD:275368
		C2H2 Zn finger	86..106	CDD:275368
		COG5048	110..522	CDD:227381
		C2H2 Zn finger	114..134	CDD:275368
		C2H2 Zn finger	142..162	CDD:275368
		C2H2 Zn finger	170..190	CDD:275368
		C2H2 Zn finger	198..218	CDD:275368
		C2H2 Zn finger	226..246	CDD:275368
		C2H2 Zn finger	254..274	CDD:275368
		C2H2 Zn finger	282..302	CDD:275368
		C2H2 Zn finger	310..330	CDD:275368
		C2H2 Zn finger	338..358	CDD:275368
		C2H2 Zn finger	366..386	CDD:275368
		COG5048	390..858	CDD:227381	56/292 (19%)
		C2H2 Zn finger	394..414	CDD:275368
		C2H2 Zn finger	422..442	CDD:275368
		C2H2 Zn finger	450..470	CDD:275368
		C2H2 Zn finger	478..498	CDD:275368
		C2H2 Zn finger	506..526	CDD:275368
		C2H2 Zn finger	534..554	CDD:275368	5/19 (26%)
		C2H2 Zn finger	562..582	CDD:275368	3/19 (16%)
		C2H2 Zn finger	590..610	CDD:275368	7/25 (28%)
		C2H2 Zn finger	618..638	CDD:275368	4/19 (21%)
		C2H2 Zn finger	646..666	CDD:275368	5/24 (21%)
		C2H2 Zn finger	674..694	CDD:275368	5/20 (25%)
		C2H2 Zn finger	702..722	CDD:275368	2/19 (11%)
		C2H2 Zn finger	730..750	CDD:275368	8/29 (28%)
		C2H2 Zn finger	758..778	CDD:275368
		C2H2 Zn finger	786..806	CDD:275368
		C2H2 Zn finger	814..834	CDD:275368
		C2H2 Zn finger	842..862	CDD:275368
		zf-H2C2_2	855..879	CDD:316026
		C2H2 Zn finger	870..890	CDD:275368
		C2H2 Zn finger	898..918	CDD:275368
		zf-H2C2_2	910..935	CDD:316026
		C2H2 Zn finger	926..946	CDD:275368
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1383726at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	1.010