Protein Alignment Arp8 and ACTL6A

DIOPT Version :9

• Sequence 1: NP_573251.1
• Gene: Arp8 / 32769
• FlyBaseID: FBgn0030877
• Length: 607
• Species: Drosophila melanogaster
• Sequence 2: NP_004292.1
• Gene: ACTL6A / 86
• HGNCID: 24124
• Length: 429
• Species: Homo sapiens
• Alignment Length: 476
• Identity: 83/476 - (17%)
• Similarity: 159/476 - (33%)
• Gaps: 149/476 - (31%)

  Fly   161 DDRILRLGAVDARNYDIHFPIQRGELNVHNEKGGSLQASMQHLERIWSYALEERLKIPLRKLGTH 225
            |...||   |...|.:...|::.|.:    |...|.||.:.|     :|.:..:.:..|.
Human    71 DTNALR---VPRENMEAISPLKNGMV----EDWDSFQAILDH-----TYKMHVKSEASLH----- 118

  Fly   226 CAVLVVNDVYVRRHLREFVT-LLLRRLGFRRCFLVQDSVASTFGAGIGYGCVVDIGAQKTSIACI 289
             .||:....:..|..||.:| |:.........||.:.:|.:.|..|...|.::|.||..|:...:
Human   119 -PVLMSEAPWNTRAKREKLTELMFEHYNIPAFFLCKTAVLTAFANGRSTGLILDSGATHTTAIPV 182

  Fly   290 EDGISQLDARVRLSYGGGDLDQVLLLLLRKCGFPYRECNVQESYVDAHLLD-------------E 341
            .||.......|:....|.       .:..:|...::|.|::  .|..:::.             :
Human   183 HDGYVLQQGIVKSPLAGD-------FITMQCRELFQEMNIE--LVPPYMIASKEAVREGSPANWK 238

  Fly   342 LKEKFCHLNAS----VCGAQEKHFNLRKHNGQWLRYTIQVGDEALMAPLALFHTELLNITGRTKA 402
            .|||...:..|    :|....:.|     ....|:.:....||.:.|.:...|.|..|
Human   239 RKEKLPQVTRSWHNYMCNCVIQDF-----QASVLQVSDSTYDEQVAAQMPTVHYEFPN------- 291

  Fly   403 VFTQQAVQDQYDCEDCFDAEYLK------ETGRKNGVRGGDILQLS----TSAGYQPRPQLPVTA 457
                     .|:|:  |.||.||      :.....|:.|..:|.:|    ||.|
Human   292 ---------GYNCD--FGAERLKIPEGLFDPSNVKGLSGNTMLGVSHVVTTSVG----------- 334

  Fly   458 DDEELIVVDQDETISNCQSQLGAQTAGGQMNSNGCYHNGQGLVLPLDQAIIQSINRLSSYETKRK 522
                                                                    :...:.:..
Human   335 --------------------------------------------------------MCDIDIRPG 343

  Fly   523 MFGSILLVGSSAKLPGLAAWLEQRISQQVQSEVNV-LIKG---MDAGMVAWKGAAIMSVLESARE 583
            ::||:::.|.:..:......|.:.:||:....:.: ||..   ::....:|.|.:|::.|.:.::
Human   344 LYGSVIVAGGNTLIQSFTDRLNRELSQKTPPSMRLKLIANNTTVERRFSSWIGGSILASLGTFQQ 408

  Fly   584 LWISQNDWQRHGLRVLRERSP 604
            :|||:.:::..|.:.:..:.|
Human   409 MWISKQEYEEGGKQCVERKCP 429

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Arp8	NP_573251.1	NBD_sugar-kinase_HSP70_actin	202..603	CDD:302596	71/432 (16%)
ACTL6A	NP_004292.1	Actin	11..429	CDD:394979	82/474 (17%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5277
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810