Protein Alignment Arp8 and ACTR3B

DIOPT Version :9

• Sequence 1: NP_573251.1
• Gene: Arp8 / 32769
• FlyBaseID: FBgn0030877
• Length: 607
• Species: Drosophila melanogaster
• Sequence 2: NP_065178.1
• Gene: ACTR3B / 57180
• HGNCID: 17256
• Length: 418
• Species: Homo sapiens
• Alignment Length: 537
• Identity: 97/537 - (18%)
• Similarity: 165/537 - (30%)
• Gaps: 207/537 - (38%)

  Fly   111 VVDNKNRLRVATPPQQLAHF------NRSSQAEKVPAPSGQMADEPWLDR-EAPVLFDDRILRLG 168
            |||...| ||......|..|      ::.:.|.|.|...|.:.|...::| ...|:|  :.||
Human    43 VVDQAQR-RVLRGVDDLDFFIGDEAIDKPTYATKWPIRHGIIEDWDLMERFMEQVVF--KYLR-- 102

  Fly   169 AVDARNYDIHFPIQRGELNVHNEKGGSLQASMQHLERIWSYALEERLKIPLRKLGTHCAVLVVND 233
               |...|.:|.:....||....:        ::|..|    :.|...:|    |.:.||..|
Human   103 ---AEPEDHYFLMTEPPLNTPENR--------EYLAEI----MFESFNVP----GLYIAVQAV-- 146

  Fly   234 VYVRRHLREFVTLLLRRLGFRRCFLVQDSVASTFGAGIGYGCVVDIGAQKTSIACIEDGISQLDA 298
                  |....:...|::|.|..                .|.|:|.|...|.:..:.:|......
Human   147 ------LALAASWTSRQVGERTL----------------TGIVIDSGDGVTHVIPVAEGYVIGSC 189

  Fly   299 RVRLSYGGGDLDQVLLLLLRKCGFPYRECNV--QESYVDAHLLDELKEKFCHLNASVCGAQEKHF 361
            ...:...|.|:...:..|||:     ||..:  ::|...|   ..:|||:|:    :|....|.|
Human   190 IKHIPIAGRDITYFIQQLLRE-----REVGIPPEQSLETA---KAIKEKYCY----ICPDIVKEF 242

  Fly   362 NLRKHN---GQWL------------RYTIQVGDEALMAPLALFHTELLNITGRTKAVFTQQAVQD 411
              .|::   .:|:            ::.|.||.|..:.|...||.|..|
Human   243 --AKYDVDPRKWIKQYTGINAINQKKFVIDVGYERFLGPEIFFHPEFAN---------------- 289

  Fly   412 QYDCEDCFDAEYLKETGRKNGVRGGDILQLSTSAGYQPRPQLPVTADDEELIVVDQDETISNCQS 476
                                                   |....:..|    ||  ||.|.||
Human   290 ---------------------------------------PDFMESISD----VV--DEVIQNC-- 307

  Fly   477 QLGAQTAGGQMNSNGCYHNGQGLVLPLDQAIIQSINRLSSYETKRKMFGSILLVGSSAKLPGLAA 541
                                     |:|              .:|.::.:::|.|.|........
Human   308 -------------------------PID--------------VRRPLYKNVVLSGGSTMFRDFGR 333

  Fly   542 WLEQ----------RISQQVQS--------EVNVLIKGMDAGMVAWKGAAIMSVLESARELWISQ 588
            .|::          |:|:::..        ||.|:...|....| |.|.::::......::..::
Human   334 RLQRDLKRVVDARLRLSEELSGGRIKPKPVEVQVVTHHMQRYAV-WFGGSMLASTPEFFQVCHTK 397

  Fly   589 NDWQRHGLRVLRERSPF 605
            .|::.:|..:.|....|
Human   398 KDYEEYGPSICRHNPVF 414

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Arp8	NP_573251.1	NBD_sugar-kinase_HSP70_actin	202..603	CDD:302596	73/435 (17%)
ACTR3B	NP_065178.1	PTZ00280	2..417	CDD:240343	97/537 (18%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5277
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900