DRSC/TRiP Functional Genomics Resources

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Protein Alignment Arp8 and POTEG

DIOPT Version :9

Sequence 1:NP_573251.1 Gene:Arp8 / 32769 FlyBaseID:FBgn0030877 Length:607 Species:Drosophila melanogaster
Sequence 2:NP_001005356.1 Gene:POTEG / 404785 HGNCID:33896 Length:508 Species:Homo sapiens


Alignment Length:292 Identity:55/292 - (18%)
Similarity:100/292 - (34%) Gaps:94/292 - (32%)


- Green bases have known domain annotations that are detailed below.


  Fly   282 QKTSIACIED-GISQLDARVR----LSYGGGDLDQVLLLLLRKCGFPYRECNVQESYVDAHLLDE 341
            :|..|..::| .:::.|.:.|    |:...|:.:.|.|||.|:|              ..::||.
Human   154 RKDLIVMLKDTDMNKKDKQKRTALHLASANGNSEVVKLLLDRRC--------------QLNILDN 204

  Fly   342 LKEKFCHLNASVCGAQEKHFNLRKH----------NGQWLRYTIQVGDEALMAPLALFHTEL--L 394
             |::.....|..|...|....|.:|          ....|.|.|...|:.:...|.|:..::  .
Human   205 -KKRTALTKAVQCREDECALMLLEHGTDPNIPDEYGNTALHYAIYNEDKLMAKALLLYGADIESK 268

  Fly   395 NITGRTKAVF-----TQQAVQ------------DQYD--------CEDCFDAEYLK--------- 425
            |..|.|..:.     .||.|:            |:|.        |  |..|..:.         
Human   269 NKHGLTPLLLGVHEQKQQVVKFLIKKKANLNALDRYGRTALILAVC--CGSASIVSLLLEQNIDV 331

  Fly   426 -------ETGRKNGVRGGDILQLSTSAGYQPRPQLPVTAD----DEELIVVDQDET-----ISNC 474
                   :|.|:..|.....:.....:.|:.:..|.|:::    :::|.:..::|:     ..|.
Human   332 SSQDLSGQTAREYAVSSHHNVICQLLSDYKEKQMLKVSSENSNPEQDLKLTSEEESQRLKGSENS 396

  Fly   475 QSQLGAQ----TAGG------QMNSNGCYHNG 496
            |.:..:|    ..||      :|..:|..|.|
Human   397 QPEEMSQEPEINKGGDRKVEEEMKKHGSTHMG 428

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Arp8NP_573251.1 NBD_sugar-kinase_HSP70_actin 202..603 CDD:302596 55/292 (19%)
POTEGNP_001005356.1 Ank_4 143..193 CDD:290365 9/38 (24%)
ANK 167..292 CDD:238125 30/139 (22%)
ANK 1 172..201 9/42 (21%)
ANK repeat 174..203 CDD:293786 9/42 (21%)
Ank_2 177..269 CDD:289560 22/106 (21%)
ANK repeat 205..236 CDD:293786 6/30 (20%)
ANK 2 205..234 6/28 (21%)
ANK 233..357 CDD:238125 20/125 (16%)
ANK repeat 238..269 CDD:293786 6/30 (20%)
ANK 3 238..267 6/28 (21%)
Ank_2 243..335 CDD:289560 17/93 (18%)
ANK repeat 271..302 CDD:293786 5/30 (17%)
ANK 4 271..300 5/28 (18%)
ANK repeat 304..335 CDD:293786 4/32 (13%)
ANK 5 304..333 4/30 (13%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 367..488 12/62 (19%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG5277
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.900

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