DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Arp8 and Bap55

DIOPT Version :9

Sequence 1:	NP_573251.1	Gene:	Arp8 / 32769	FlyBaseID:	FBgn0030877	Length:	607	Species:	Drosophila melanogaster
Sequence 2:	NP_611209.1	Gene:	Bap55 / 36956	FlyBaseID:	FBgn0025716	Length:	425	Species:	Drosophila melanogaster

Alignment Length:	597	Identity:	104/597 - (17%)
Similarity:	188/597 - (31%)	Gaps:	215/597 - (36%)

- Green bases have known domain annotations that are detailed below.

  Fly    36 IVIHPGSQHLRIGRAADLNPLTLLHAVAYRRRPGASDRPHHDPLLPPLDNVNSNSGLMVEFEEQR 100
            :|..||...||:|.|.:.:|...:.:|.   ..||:...:.||.....:|...|:.     ::::
  Fly    16 LVFDPGHHSLRVGYAQEDSPKAEIPSVV---GIGAAPETNLDPETKTDNNATPNNA-----DQRK 72

  Fly   101 LVVSRILQHCVVDNKNRLRVATPPQQLAHFNRSSQAEKVPAPSGQMADEPWLDREAPVLFDDRIL 165
            ..|                               ....|..|...|..:.:             :
  Fly    73 FYV-------------------------------DTNYVTVPRSNMEVQTY-------------M 93

  Fly   166 RLGAVDARNYDIHFPIQRGELNVHNEKGGSLQASMQHLERIWSYALEERLKIPLRKLGTHCAVLV 230
            :.|.:|  |:|:                         .|::..||....::   .:...|..:..
  Fly    94 KDGMID--NWDL-------------------------FEKVIDYAYANVIQ---SEPEYHPVLFS 128

  Fly   231 VNDVYVRRHLREFVTLLLRRLGFRRCFLVQDSVASTFGAGIGYGCVVDIGAQKTSIACIEDGISQ 295
            .....||.:..:...|:..:......|||:::|.:.|.:|.....|||.||..||...:.:|...
  Fly   129 EASWNVRNNREKLTELMFEKYNVPAFFLVKNAVLAAFSSGRATALVVDSGATHTSAVPVHEGYVL 193

  Fly   296 LDARVRLSYGGGDLDQVLLLLLRKCGFPYRECNVQESYVDAHLLDELKEKFCHLNASVCGAQEK- 359
            ..|.|:...||              .|..|:|   ..:::.|.:| |...:...:..|...::.
  Fly   194 SQAVVKSPLGG--------------DFLSRQC---RQHLEKHGID-LSPVYKIASKDVVKERDNG 240

  Fly   360 HFNLRK----HNGQWLRYTIQV----------------GDEALMAPLALFHTELLNITGRTKAVF 404
            .|.|||    ....|..|.:|:                .||.:.|.:...|.|..|       .:
  Fly   241 RFTLRKLPENLTQSWQNYMLQLMMQDFQMNVLQVLENPFDERVAAQIPTVHYEFPN-------GY 298

  Fly   405 TQQAVQDQYD-CEDCFDAEYLKETGRKNGVRGGDILQLSTSAGYQPRPQLPVTADDEELIVVDQD 468
            .|....:::. .|..||          |.:.|...| .|||.|                 :.|.|
  Fly   299 HQDFGSERFKIAESLFD----------NAMLGAGQL-ASTSVG-----------------MCDAD 335

  Fly   469 ETISNCQSQLGAQTAGGQMNSNGCYHNGQGLVLPLDQAIIQSINRLSSYETKRKMFGSILLVGSS 533
            ..:|                                                  :|||:::.|.:
  Fly   336 VRLS--------------------------------------------------LFGSVVVTGGN 350

  Fly   534 AKLPGLAAWLEQRISQQVQSEVNVLIKGMDA-GMV-----AWKGAAIMSVLESARELWISQNDWQ 592
            ..|.|....|.:.:  |:::..|..:|.:.| |.|     ||.|.:|::.:.:.:::|||..:::
  Fly   351 TLLQGFPERLNRDL--QLRAPSNTRLKMISANGSVERRFGAWIGGSILASIGTFQQMWISSQEYE 413

  Fly   593 RHGLRVLRERSP 604
            ..|...:..:.|
  Fly   414 EAGKSQVERKCP 425

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Arp8	NP_573251.1	NBD_sugar-kinase_HSP70_actin	202..603	CDD:302596	80/428 (19%)
Bap55	NP_611209.1	Actin	13..425	CDD:394979	103/595 (17%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45467796
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5277
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11937
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.930