DRSC/TRiP Functional Genomics Resources

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Protein Alignment Arp8 and Actl7a

DIOPT Version :9

Sequence 1:NP_573251.1 Gene:Arp8 / 32769 FlyBaseID:FBgn0030877 Length:607 Species:Drosophila melanogaster
Sequence 2:NP_001011973.1 Gene:Actl7a / 298017 RGDID:1304697 Length:440 Species:Rattus norvegicus


Alignment Length:464 Identity:90/464 - (19%)
Similarity:159/464 - (34%) Gaps:153/464 - (32%)


- Green bases have known domain annotations that are detailed below.


  Fly   141 APSGQMADEPWLDREAPVLFDDRILRLGAVDARNYDIHF----PIQRGELNVHNEKGGSLQASMQ 201
            |.:|....|.::.||   ||             |.|||.    |::.|           :.....
  Rat   112 AKTGDNRKETFVGRE---LF-------------NPDIHLKLVNPLRHG-----------IIVDWD 149

  Fly   202 HLERIWSYALEERLKIPLRKLGTHCAVLVVNDVYVRRHL--REFVTLLLRRLGFRRCFLVQDSVA 264
            .::.||.|...:.:||...:   | ||| |:|..:..|.  .::..:|..........:...|..
  Rat   150 TVQDIWEYLFRQEMKIAPEE---H-AVL-VSDPPLSPHTNREKYAEMLFETFNTPAMHIAYQSRL 209

  Fly   265 STFGAGIGYGCVVDIGAQKTSIACIEDGISQLDARVRLSYGGGDLDQVLLLLLRKCGFPYRECNV 329
            |.:..|...|.||::|...:.:..|.:|........||.|.|.||...|:.|:..||..:.|.::
  Rat   210 SMYSYGRTSGLVVEVGHGVSYVVPIYEGYPLPSITGRLDYAGSDLTNYLMNLMNNCGKHFSEDHL 274

  Fly   330 QESYVDAHLLDELKEKFCHLNASVCGAQEKHFNLRKHNGQWLRYTIQVGDEALMAPLALFHTELL 394
            .       :::::|.|.|.:  ::...:||.....:|.   :.||:..|.|..:.          
  Rat   275 S-------IVEDIKTKCCFV--ALDPIEEKKIPPSEHE---IHYTLPDGKEIRLG---------- 317

  Fly   395 NITGRTKAVFTQQAVQDQYDCEDCFDAEYLKETGRKNGVRGGDILQLSTSAGYQPRPQLPVTADD 459
                           |:::.|.:.|                           ::|          
  Rat   318 ---------------QERFLCSEMF---------------------------FKP---------- 330

  Fly   460 EELIVVDQDETISNCQSQLGAQTAGGQMNSNGCYHNGQGLVLPLDQAIIQSINRLSSYETKRKMF 524
                     ..|.:.|..|..||                         :..:|: .....||.:.
  Rat   331 ---------SLIKSMQLGLHTQT-------------------------VSCLNK-CDIALKRDLM 360

  Fly   525 GSILLVGSSAKLPGLAAWLEQRISQQVQS---EVNVLIKGMDAGMVAWKGAAIMSVLESARELWI 586
            |:|||.|.|..|.|....|::.:|....:   :||||   .:.....|.|.:|::.|:..:.||:
  Rat   361 GNILLCGGSTMLRGFPNRLQKELSSMCPNDTPQVNVL---PERDTAVWTGGSILASLQGFQPLWV 422

  Fly   587 SQNDWQRHG 595
            .:.:::.||
  Rat   423 HRLEYEEHG 431

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Arp8NP_573251.1 NBD_sugar-kinase_HSP70_actin 202..603 CDD:302596 77/399 (19%)
Actl7aNP_001011973.1 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..27
ACTL7A_N 6..70 CDD:293445
Required for interaction with TES. /evidence=ECO:0000250 36..56
NBD_sugar-kinase_HSP70_actin 72..440 CDD:302596 90/464 (19%)
ACTIN 74..440 CDD:214592 90/464 (19%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG5277
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
21.810

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