Protein Alignment Arp8 and ACTL9

DIOPT Version :9

• Sequence 1: NP_573251.1
• Gene: Arp8 / 32769
• FlyBaseID: FBgn0030877
• Length: 607
• Species: Drosophila melanogaster
• Sequence 2: NP_848620.3
• Gene: ACTL9 / 284382
• HGNCID: 28494
• Length: 416
• Species: Homo sapiens
• Alignment Length: 605
• Identity: 109/605 - (18%)
• Similarity: 186/605 - (30%)
• Gaps: 208/605 - (34%)

  Fly     1 MQRSRASSTSSGRHPAPPPIGLPQPQAQPLEAPKIIVIHPGSQHLRIGRAADLNPL-TLLHAVAY 64
            |..||..|:.|               ...||||:     ||.           ||. .:::....
Human     1 MDASRPKSSES---------------QSSLEAPR-----PGP-----------NPSPNVVNKPLQ 34

  Fly    65 RRRPG-ASDRPHHDPLLPPLDNVNSNSGLMVEFEEQRLVVSRILQHCVVDNKNRLRVATPPQQLA 128
            |..|| .:||      |||              :...:|:......|.|....:   |:|...:|
Human    35 RDSPGMVADR------LPP--------------KTGAVVIDMGTGTCKVGFAGQ---ASPTYTVA 76

  Fly   129 HFNRSSQAEKVPAPSGQMADEPWLDREAPVLFDDRILRLGAVDARNYDIHFPIQRGELNVHNEKG 193
            .. ...|.:| ||.|||...:.::...|.||.:..:::             |::.|
Human    77 TI-LGCQPKK-PATSGQSGLQTFIGEAARVLPELTLVQ-------------PLRSG--------- 117

  Fly   194 GSLQASMQHLERIWSYALEERLKIPLRKLGTHCAVLVVND--VYVRRHLREFVTLLLRRLGFRRC 256
              :.......|.||.:.||..|::     .||...|:.:|  .....:..:.|.:....|.....
Human   118 --IVVDWDAAELIWRHLLEHDLRV-----ATHDHPLLFSDPPFSPATNREKLVEVAFESLRSPAM 175

  Fly   257 FLVQDSVASTFGAGIGYGCVVDIGAQKTSIACIEDGISQLDARVRLSYGGGDLDQVLLLLLRKCG 321
            ::...||.|.:..|...|.|||.|...|....:..|.:.|.|..||...|.:|...|..:|.:.|
Human   176 YVASQSVLSVYAHGRVSGLVVDTGHGVTYTVPVFQGYNLLHATERLDLAGNNLTAFLAEMLLQAG 240

  Fly   322 FPYRECNVQESYVDAHLLDELKEKFCHL-----NASVCGAQEKHFNLRKHNGQWLRYTIQVGDEA 381
            .|..:       .|..|::.:|..:|::     .......||....|:..:|:    |:.:|.|.
Human   241 LPLGQ-------QDLDLVENIKHHYCYVASDFQKEQARPEQEYKRTLKLPDGR----TVTLGKEL 294

  Fly   382 LMAPLALFHTELLNITGRTKAVFTQQAVQDQYDCEDCFDAEYLKETGRKNGVRGGDILQLSTSAG 446
            ...|..||:.
Human   295 FQCPELLFNP------------------------------------------------------- 304

  Fly   447 YQPRPQLPVTADDEELIVVDQDETISNCQSQLGAQTAGGQMNSNGCYHNGQGLVLPLDQAIIQSI 511
                |::|                        |....|                  |.....||:
Human   305 ----PEVP------------------------GLSPVG------------------LSTMAKQSL 323

  Fly   512 NRLSSYETKRKMFGSILLVGSSAKLPGLAAWLEQRISQQVQSEVNVLIKGMDA-GMVAWKGAAIM 575
            .:| |.|.:..:..::||.|.|:...|........:.:.:.:|.:|::..... ....|.|.:|:
Human   324 RKL-SLEMRADLAQNVLLCGGSSLFTGFEGRFRAELLRALPAETHVVVAAQPTRNFSVWIGGSIL 387

  Fly   576 SVLESARELWISQNDWQRHG 595
            :.|.:.:..|:.:..::..|
Human   388 ASLRAFQSCWVLREQYEEQG 407

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Arp8	NP_573251.1	NBD_sugar-kinase_HSP70_actin	202..603	CDD:302596	70/402 (17%)
ACTL9	NP_848620.3	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..34		13/63 (21%)
		NBD_sugar-kinase_HSP70_actin	49..416	CDD:302596	88/506 (17%)
		ACTIN	49..415	CDD:214592	88/506 (17%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5277
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900